Anti-Infective – Fluoroquinolones
Included In This Lesson
Outline
Overview
- Overview
- Bacterial agents
- Types
- Norfloxacin (Noroxin)
- Ciprofloxacin (Cipro)
- Levofloxacin (Levaquin)
- Moxifloxacin (Avelox)
- Gatifloxacin (Tequin)
- Gemifloxacin (Factive)
- Mechanism of Action
- Destroy bacteria by altering their DNA
- Kill gram – / gram + organisms
- Indications
- Urinary tract infections
- Respiratory infections / Pneumonia
- Sexually transmitted infections (STIs)
- Bone and joint infections
- Prostate infections
- Contraindications
- Drug allergy
- Cardiac function
- Dysrhythmias
- Interactions
- Antacids
- Iron
- Zinc preparations
- Sucralfate
- Magnesium / Calcium
- Oral anticoagulants
Transcript
Hey there, and today’s we are going to discuss fluoroquinolones, which are a certain type of antibiotic class.
Alright, let’s review. Fluoroquinolones are bactericidal, meaning that these antibiotics KILL bacteria. They don’t simply suppress bacterial reproduction.
Fluoroquinolones all end in -FLOXACIN, which is an easy way to remember this drug class.
The mechanism of action that causes these antibiotics to work is related to their ability to alter bacterial DNA. Fluoroquinolones are used to treat gram +/- organisms.
Indications for fluoroquinolones include urinary tract infections, respiratory infections, sexually transmitted infections, bone/joint infections and prostate infections. The top three indications can be remember by URS.
Contraindications for fluoroquinolones include drug allergy and cardiac dysrhythmias. If your patient has a past medical history of ventricular tachycardia, for example, this drug wouldn’t be a good choice. Any cardiac dysrhythmia history would be a concern regarding this antibiotic use.
Some other medications that can Interact with fluoroquinolones include sucralfate, antacids, iron, magnesium, calcium, oral anticoagulants and zinc preparations. An easy way to remember these is SAIMOZ.
Psychiatric side effects for fluoroquinolones include depression and anxiety.
Sensation and muscle side effects for fluoroquinolones include sensation changes and swelling, pain and tendon rupture. There isn’t a definitive reason, researchers speculate it can be linked to mitochondrial damage, likely oxidative stress.
Cardiovascular side effects for fluoroquinolones include aortic tear and rupture. Signs and symptoms include sudden, severe chest pain, hypotension, flank or back pain. These patients often die before they are able to seek surgical intervention.
Endocrine side effects for fluoroquinolones include hypoglycemia. If your patient has a baseline of hypoglycemia, this will exacerbate their condition.
Priority nursing concepts for fluoroquinolones include pharmacology and infection control.
Alright let’s review fluoroquinolones. These antibiotics end in -FLOXACIN. Top three indications can be remembered by URS (urine, respiratory and sexual transmitted infections). Contraindications include drug allergies and cardiac dysrhythmias. This drug class has many interactions, which can be remembered by SAIMOZ (sucralfate, antacids, iron, magnesium/calcium, oral anticoagulants and zinc preparations). Lastly side effects include – depression and anxiety / sensation changes and swelling, pain and tendon rupture / aortic tear and rupture / hypoglycemia.
You know now the important details regarding fluoroquinolones. Now, go out and be your best self today and as always, Happy Nursing!
Tiona RN
Concepts Covered:
- Studying
- Medication Administration
- Adult
- Emergency Care of the Cardiac Patient
- Intraoperative Nursing
- Microbiology
- Cardiac Disorders
- Vascular Disorders
- Nervous System
- Upper GI Disorders
- Central Nervous System Disorders – Brain
- Immunological Disorders
- Fundamentals of Emergency Nursing
- Dosage Calculations
- Understanding Society
- Circulatory System
- Concepts of Pharmacology
- Hematologic Disorders
- Newborn Care
- Adulthood Growth and Development
- Disorders of Pancreas
- Postoperative Nursing
- Pregnancy Risks
- Neurological
- Postpartum Complications
- Noninfectious Respiratory Disorder
- Peripheral Nervous System Disorders
- Learning Pharmacology
- Prenatal Concepts
- Tissues and Glands
- Developmental Considerations
- Factors Influencing Community Health
- Childhood Growth and Development
- Prenatal and Neonatal Growth and Development
- Developmental Theories
- Basic
- Neonatal
- Pediatric
- Gastrointestinal
- Newborn Complications
- Labor Complications
- Fetal Development
- Terminology
- Labor and Delivery
- Postpartum Care
- Communication
- Basics of Mathematics
- Statistics
- Basics of Sociology
- Cardiovascular
- Shock
- Shock
- Disorders of the Posterior Pituitary Gland
- Endocrine
- Disorders of the Thyroid & Parathyroid Glands
- Liver & Gallbladder Disorders
- Lower GI Disorders
- Respiratory
- Delegation
- Perioperative Nursing Roles
- Acute & Chronic Renal Disorders
- Respiratory Emergencies
- Disorders of the Adrenal Gland
- Documentation and Communication
- Preoperative Nursing
- Legal and Ethical Issues
- Oncology Disorders
- Female Reproductive Disorders
- Musculoskeletal Trauma
- Renal Disorders
- Male Reproductive Disorders
- Sexually Transmitted Infections
- Infectious Respiratory Disorder
- Integumentary Disorders
- Emergency Care of the Trauma Patient
- Urinary Disorders
- Musculoskeletal Disorders
- EENT Disorders
- Neurological Emergencies
- Disorders of Thermoregulation
- Neurological Trauma
- Basics of NCLEX
- Integumentary Important Points
- Multisystem
- Test Taking Strategies
- Urinary System
- Emergency Care of the Neurological Patient
- Central Nervous System Disorders – Spinal Cord
- Respiratory System
- Emergency Care of the Respiratory Patient
- Cognitive Disorders
- Anxiety Disorders
- Depressive Disorders
- Trauma-Stress Disorders
- Substance Abuse Disorders
- Bipolar Disorders
- Psychotic Disorders
- Concepts of Mental Health
- Eating Disorders
- Personality Disorders
- Health & Stress
- Psychological Emergencies
- Somatoform Disorders
- Prioritization
- Community Health Overview
- Gastrointestinal Disorders
- Integumentary Disorders
- Respiratory Disorders
- Neurologic and Cognitive Disorders
- Renal and Urinary Disorders
- Infectious Disease Disorders
- EENT Disorders
- Hematologic Disorders
- Cardiovascular Disorders
- Musculoskeletal Disorders
- Endocrine and Metabolic Disorders
- Oncologic Disorders
- Behavior
- Emotions and Motivation
- Growth & Development
- Intelligence and Language
- Psychological Disorders
- State of Consciousness
- Note Taking
- Concepts of Population Health
- Basics of Human Biology