Nervous System Anatomy

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Nervous System Anatomy (Image)
Neuron Anatomy (Image)
Nerve Membranes (Image)
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Outline

Overview

  1. General Function
    1. Coordinates and integrates body functions
    2. Electrochemical communications
      1. Nerve impulses
      2. Action potentials (AP)
    3. Properties of N.S.
      1. Irritability/excitability → Ability to respond to stimuli
      2. Conductivity → Transmission of AP
    4. Sequence of Events
      1. Respond to a stimulus
      2. Convert stimulus into AP
      3. Transmit AP over appropriate pathways
      4. Produce an action

Nursing Points

General

  1. Divisions
    1. Central—Brain and Spinal Cord
    2. Peripheral
      1. Somatic — skeletal muscle contraction
        1. Spinal nerves and associated ganglia
      2. Autonomic — internal organs (involuntary)
        1. Autonomic nerves and associated ganglia
        2. Sympathetic
        3. Parasympathetic
  2. Microscopic Anatomy
    1. Neuron or nerve cell
      1. Basic unit of function of the N.S.
      2. Cannot divide
    2. Glial cells  (See Neuro Anatomy lesson in Neuro Course)
      1. More numerous
      2. Can divide
        1. Uncontrolled cell division → tumor → Glioma
    3. Schwann cell
      1. Insulator
      2. Increases speed of AP
    4. White fibrous CT
      1. Largely in spinal cord and nerves
      2. Hold neurons together
  3. Neuron
    1. Cell body
      1. Where metabolic activity occurs
      2. Nucleus
      3. Nucleolus
      4. Cytoplasm
        1. Mitochondria
        2. Golgi apparatus
          1. Produces vesicles
        3. Nissl bodies
          1. Protein synthesis
          2. RER + RNA
    2. Fibers — extend off cell body
      1. Dendrite
        1. 1-200 per cell body
        2. short
        3. Transmit AP to cell body
      2. Axon
        1. 1 per neuron
        2. Long
          1. Longest are 2-3 feet long and are located in the back of the leg innervating the gastrocnemius and adjacent muscles
        3. Axon terminals / filaments
          1. Terminate
            1. Synaptic knob
            2. Bouton
            3. End foot
          2. Contain synaptic vesicles
            1. Carry neurotransmitters
          3. Also contain mitochondria
    3. Neurofibrils (intermediate filaments & microtubules)
      1. Found in all parts of neuron
      2. Maintain shape of neuron
      3. In axon — pathway for movement of:
        1. Vesicles
          1. Hold neurotransmitters and other chemicals
        2. Mitochondria
        3. Acetylcholine esterase
          1. Enzyme to stop action of Acetylcholine
    4. Functional classification
      1. Afferent (sensory) neurons
        1. Respond to stimuli
        2. send AP to CNS
      2. Efferent (motor) neurons
        1. Receive AP from sensory neurons
        2. Send AP to:
          1. Muscles
          2. Glands
        3. Always found in CNS
    5. Types of Axons
      1. Myelinated (PNS only)
        1. Schwann cells wrap around axon
          1. Produce a myelin sheath
        2. Nodes of Ranvier — spaces between Schwann cells
      2. Unmyelinated
        1. Multiple axons associated with single Schwann cells
          1. Schwann cells cannot rotate around all axons therefore no myelin sheath is produced
    6. Nerve Membranes
      1. Epineurium — WFCT
        1. Around outside of a group of fascicles
      2. Perineurium – WFCT
        1. Surrounds fascicle — group of nerve cells
      3. Endoneurium – Loose Areolar CT
        1. Surrounds individual neurons
      4. Function of membranes
        1. Maintains nerve anatomical structure
        2. Provide pathway for BVs
  4. Glial cells
    1. Oligodendrocyte
      1. Produces myelin sheaths in CNS
    2. Microgliocytes
      1. “Macrophage of Nervous System”
      2. Destroy bacteria and damaged tissue by phagocytosis
    3. Astrocytes
      1. Attach to neuron and blood capillaries
      2. Contribute to the blood-brain barrier
        1. Blood-brain barrier
          1. Endothelium of capillaries in CNS
          2. Tight junctions
          3. Certain substances can’t pass
          4. Some water-soluble substances have transport mechanisms
            1. Sodium, potassium, glucose
            2. Penicillin is water-soluble, but cannot pass the barrier
          5. Lipid-soluble substances easily pass the blood-brain barrier
            1. Alcohol, anesthetics, heroin
            2. Erythromycin is an antibiotic that crosses easily
      3. Help control potassium in ECF
    4. Ependymal cells
      1. Create Cerebrospinal Fluid (CSF)
        1. Fills internal spaces (ventricles) in brain
        2. Regulates chemical concentration
      2. Locations
        1. Line outer wall of ventricle
        2. Choroid plexus
          1. Group of capillaries covered by ependymal cells
      3. Ciliated
        1. Helps move CSF in/around the brain

References
Betts, J.G., et al. (2017). Anatomy and physiology. Houston, TX: OpenStax, Rice University. Retrieved from https://openstax.org/details/books/anatomy-and-physiology?Book%20details

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Transcript

Okay guys, in this lesson, we’re going to talk about the anatomy of the nervous system.

So, first I want to make sure you understand the purpose of the nervous system. This is what helps us coordinate and integrate all of our body functions. That’s everything from moving to breathing to digesting our food. It’s all coordinated through electrochemical signals that send signals from the nervous system out to other parts of the body. Now there are two main properties you need to know about the nervous system. One is irritability. That means that it can respond to some sort of stimulus. Another word is excitable. So it gets a stimulus and responds by starting a signal. Those signals are called Action Potentials. You’ll see me write AP. The second property is conductivity. This means that it can then take that signal or Action Potential and transmit it down nerve pathways to get it where it needs to go. So it ‘conducts’ the signal.

So let’s see what it looks like when it sends these electrochemical signals – again, remember they’re called Action Potentials or AP. So first the nerve will get a stimulus and respond to that stimulus – this could be almost anything. Like a pain sensation or stretching of the stomach. Then it converts that stimulus into an Action Potential – again that’s that irritability or excitability property. Then it’s going to send that action potential down a certain pathway, depending on what it’s trying to accomplish, and when it gets there, it’s going to produce an action. So an example might be – you touch a hot stove – so the pain is the stimulus. That tells your brain to initiate and send an action potential down your arm to pull your hand away. These types of electrochemical signals are happening constantly throughout your body and that’s how everything stays coordinated and working right.

So before we get into the cellular anatomy, I want to talk about the overall divisions of the nervous system. You’re going to see these terms a LOT moving forward, so make sure that you really understand this part. First, we have the Central and Peripheral Nervous Systems. The Central Nervous System or CNS is the Brain and Spinal Cord. So, if you’re looking at the nervous system as a whole – it is literally in the center. This is where the majority of our control centers are. Then we have Peripheral Nervous System or PNS, which is everything else. It is then divided into the somatic and autonomic nervous systems. When you see somatic I want you to think skeletal muscle and think voluntary actions. Autonomic – think “Automatic” – these are the unconscious involuntary things that happen in our bodies. So, somatic voluntary, autonomic involuntary. ONE more division – and this is the part you’re going to see a LOT. The Autonomic Nervous System is divided again into Sympathetic and Parasympathetic. For now – here’s what you need to know: Sympathetic Nervous System is “fight or flight” – this is what helps us fight off an attack or flee away from it – so all our senses are heightened, our heart rate and blood pressure go up, and non-essential functions like digestion are slowed down. The Parasympathetic Nervous System is “rest and digest” – so this slows us down a little and allows us to do the things we couldn’t do when we were fighting – like digestion and reproduction. So – fight or flight and rest and digest.

Now let’s talk generally about the cells of the nervous system. We have neurons and we have glial cells. The Neuron is the basic unit of the nervous system. If signals are being sent somewhere, it’s a neuron that’s involved. We classify them by their function – we have afferent and efferent neurons. Afferent is sensory, so it receives signals from the body. Efferent is motor – so it sends signals from the brain out to the organs to produce an action. You can remember this with the mnemonic SAME – S – sensory, A- afferent, M- motor, E – efferent. As far as glial cells there are quite a few types. We talk about these in detail in the neuro section of the med-surg course, and we’ve provided some detail in your outline. Big difference you’ll see here is that neurons don’t undergo mitosis – or cell division – and glial cells do.

Now, since the neuron is the basic unit of the nervous system – let’s talk about the different parts of the neuron and the role they play. This larger part here is called the cell body – this is where you’ll find the nucleus as well as other cellular structures like the mitochondria, etc. These finger like projections are called dendrites, this is what will receive the signal from another neuron. The long thin structure is called the axon – depending on where this particular neuron is in the body, the axon could be up to 2 feet long! Along the length of the axon, you may see what’s called a myelin sheath – it’s formed by these cells called Schwann cells. Now – you only have a myelin sheath if the cell wraps all the way around one axon. If you try to wrap the cell around multiple axons, it’s not actually going to create the myelin sheath because it can’t wrap all the way around them. The purpose of the myelin sheath is to make the transmission of the action potential much smoother down the length of the axon. So if you HAVE the myelin sheath, it’s called myelinated – otherwise you’d call it unmyelinated. We also have these little gaps between each of the Schwann cells in our myelinated axons – those are called Nodes of Ranvier – and their purpose is to speed up the signal by actually allowing it to JUMP from node to node. So we not only get a smoother signal, but a faster one. And finally, when the signal gets to the other end of the axon, it’s going to come to these axon terminals – also known as an “end foot”. So picture another neuron right on the other side of this terminal. The terminal backs right up to the dendrites on the other side – sends the signal across – and continues the action potential down the next neuron.

Now, in the lesson on nerve transmission, we’re going to talk in detail about how this signal goes from neuron to neuron – but the main thing I want you to see here is that the signal comes down the axon, to the terminal, and passes to another neuron. In that axon terminal we have little vesicles that hold our neurotransmitters – and that is what helps us send the signal. Again, check out the lesson on nerve transmission to see more details about that.

Last thing I want to review quickly is the membranes. If you’ve already watched the muscle and bone lessons, this is going to feel very familiar to you. You’ll have an individual neuron, covered in endoneurium – then a group of those bunched together in a fascicle by perineurium, then a group of fascicles held together by the epineurium. This is white fibrous connective tissue – and sometimes you might even see tiny blood vessels grouped in here as well.

So let’s recap what we’ve learned about the nervous system. Its main function is to receive and transmit electrochemical signals throughout the body to coordinate and integrate body functions. It is divided into the Central and Peripheral Nervous System, which is further divided into the Somatic and Autonomic Nervous Systems – which is divided ONE more time into the Sympathetic and Parasympathetic Nervous Systems. We have the neuron, which is the basic unit of the nervous system, as well as some glial cells in the central nervous system. And remember that at the end of the neuron is the axon terminal, which is where all the magic happens to send signals to other neurons. Make sure you check out the nerve transmission lesson to see more details about how that happens.

Check out the resources attached to this lesson as well. Now, go out and be your best selves today. And, as always, happy nursing!

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Concepts Covered:

  • Disorders of the Posterior Pituitary Gland
  • Disorders of the Thyroid & Parathyroid Glands
  • Disorders of Pancreas
  • Prenatal Concepts
  • Tissues and Glands
  • Pregnancy Risks
  • Health & Stress
  • Emergency Care of the Cardiac Patient
  • Vascular Disorders
  • Terminology
  • Studying
  • Female Reproductive Disorders
  • Disorders of the Adrenal Gland
  • Endocrine System
  • Oncology Disorders
  • Eating Disorders
  • Substance Abuse Disorders
  • Shock
  • Respiratory Disorders
  • Male Reproductive Disorders
  • Gastrointestinal Disorders
  • Upper GI Disorders
  • Liver & Gallbladder Disorders
  • Digestive System
  • Newborn Complications
  • Neurologic and Cognitive Disorders
  • Emergency Care of the Trauma Patient
  • Disorders of Thermoregulation
  • Hematologic Disorders
  • Lower GI Disorders
  • Immunological Disorders
  • Anxiety Disorders
  • Endocrine and Metabolic Disorders
  • Urinary Disorders
  • Cardiac Disorders
  • Central Nervous System Disorders – Brain
  • Nervous System
  • Intraoperative Nursing
  • Medication Administration
  • Urinary System
  • Musculoskeletal Trauma
  • Cognitive Disorders
  • Acute & Chronic Renal Disorders
  • Noninfectious Respiratory Disorder
  • Somatoform Disorders
  • Microbiology
  • Adult
  • Multisystem
  • Neurological
  • Emergency Care of the Neurological Patient
  • Peripheral Nervous System Disorders
  • Neurological Trauma
  • Central Nervous System Disorders – Spinal Cord
  • Neurological Emergencies
  • Musculoskeletal Disorders
  • Preoperative Nursing
  • Skeletal System
  • Musculoskeletal Disorders
  • Communication
  • Learning Pharmacology

Study Plan Lessons

03.05 Endocrine Practice Questions for CCRN Review
Diabetes Mellitus for Progressive Care Certified Nurse (PCCN)
Factors That Can Put a Pregnancy at Risk Nursing Mnemonic (RIBCAGE)
Glands
Glucose Tolerance Test (GTT) Lab Values
Health & Stress
Hypertension (Uncontrolled) and Hypertensive Crisis for Progressive Care Certified Nurse (PCCN)
Hypoglycemia for Progressive Care Certified Nurse (PCCN)
Metabolic & Endocrine Module Intro
Metabolic & Endocrine Terminology
Metabolic/Endocrine Course Introduction
Mnemonic for Organ Systems (MR DICE RUNS)
Nursing Care and Pathophysiology for Menopause
Nursing Care Plan (NCP) for Addison’s Disease (Primary Adrenal Insufficiency)
Nursing Care Plan (NCP) for Hyperthyroidism
Nursing Care Plan (NCP) for Osteoporosis
Nutritional Requirements
Pancreas
Pharmacology Terminology
Pituitary Adenoma
Potassium-K (Hyperkalemia, Hypokalemia)
Thyroid Cancer
Urinalysis (UA)
Anti-Infective – Carbapenems
Anti-Infective – Macrolides
Anti-Infective – Sulfonamides
Appendicitis
Bariatric Surgeries
Celiac Disease
Cirrhosis for Certified Emergency Nursing (CEN)
Colonoscopy
Colorectal Cancer (colon rectal cancer)
Constipation and Encopresis (Incontinence)
Cystic Fibrosis (CF)
Digestion & Absorption
Digestive Terminology
Discomforts of Pregnancy
Endoscopy & EGD
Erythroblastosis Fetalis
Famotidine (Pepcid) Nursing Considerations
Gastritis
Gastrointestinal (GI) Bleed Concept Map
Gastrointestinal (GI) Course Introduction
Gastrointestinal Trauma for Certified Emergency Nursing (CEN)
Hemorrhagic Fevers for Certified Emergency Nursing (CEN)
Hyperbilirubinemia (Jaundice)
Imperforate Anus
Intussusception
Iron (Fe) Lab Values
Liver Function Tests
Lower Gastrointestinal (GI) Module Intro
Nursing Care Plan (NCP) for Abdominal Pain
Nursing Care Plan (NCP) for Acquired Immune Deficiency Syndrome (AIDS)
Nursing Care Plan (NCP) for Addison’s Disease (Primary Adrenal Insufficiency)
Nursing Care Plan (NCP) for Anemia
Nursing Care Plan (NCP) for Anxiety
Nursing Care Plan (NCP) for Appendicitis
Nursing Care Plan (NCP) for Bowel Obstruction
Nursing Care Plan (NCP) for Cholecystitis
Nursing Care Plan (NCP) for Colorectal Cancer (Colon Cancer)
Nursing Care Plan (NCP) for Constipation / Encopresis
Nursing Care Plan (NCP) for Cystic Fibrosis
Nursing Care Plan (NCP) for Dehydration & Fever
Nursing Care Plan (NCP) for Diverticulosis / Diverticulitis
Nursing Care Plan (NCP) for GI (Gastrointestinal) Bleed
Nursing Care Plan (NCP) for Hyperemesis Gravidarum
Nursing Care Plan (NCP) for Imperforate Anus
Nursing Care Plan (NCP) for Inflammatory Bowel Disease (Ulcerative Colitis / Crohn’s Disease)
Nursing Care Plan (NCP) for Intussusception
Nursing Care Plan (NCP) for Nutrition Imbalance
Nursing Care Plan (NCP) for Ovarian Cancer
Nursing Care Plan (NCP) for Pancreatitis
Nursing Care Plan (NCP) for Peptic Ulcer Disease (PUD)
Nursing Care Plan (NCP) for Sepsis
Nursing Care Plan (NCP) for Stomach Cancer (Gastric Cancer)
Nursing Care Plan (NCP) for Urinary Tract Infection (UTI)
Nursing Care Plan for Hiatal Hernia
Nursing Care Plan for Liver Cancer
Nursing Care Plan for Scleroderma
Nursing Case Study for Colon Cancer
Nutrition (Diet) in Disease
Omphalocele
Pediatric Gastrointestinal Dysfunction – Diarrhea
Pharmacology Terminology
Physiological Changes
Thromboembolic Disease- Deep Vein Thrombosis (DVT) for Certified Emergency Nursing (CEN)
Total Bilirubin (T. Billi) Lab Values
Umbilical Hernia
Upper Gastrointestinal (GI) Module Intro
Nursing Care Plan (NCP) for Eating Disorders (Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder)
Nursing Care Plan (NCP) for Hashimoto’s Thyroiditis
Nursing Care Plan (NCP) for Hyperparathyroidism
Nutrition Assessments
Alcohol Withdrawal (Addiction)
Altered Mental Status Nursing Mnemonic (AEIOU TIPS)
Ammonia (NH3) Lab Values
Autonomic Nervous System (ANS)
Barbiturates
Bowel Perforation for Certified Emergency Nursing (CEN)
Calcium and Magnesium Imbalance for Certified Emergency Nursing (CEN)
Chemotherapy Patients
Complications of Immobility
Day in the Life of a Med-surg Nurse
Dementia Nursing Mnemonic (DEMENTIA)
Fibromyalgia
Head to Toe Nursing Assessment (Physical Exam)
Meds for Alzheimers
Nuclear Medicine
Nursing Care and Pathophysiology for Hypothyroidism
Nursing Care and Pathophysiology of Chronic Kidney (Renal) Disease (CKD)
Nursing Care Plan (NCP) for Anaphylaxis
Nursing Care Plan (NCP) for Aspiration
Nursing Care Plan (NCP) for Celiac Disease
Nursing Care Plan (NCP) for Eating Disorders (Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder)
Nursing Care Plan (NCP) for Encephalopathy
Nursing Care Plan (NCP) for Endocarditis
Nursing Care Plan (NCP) for Hashimoto’s Thyroiditis
Nursing Care Plan (NCP) for Hyperparathyroidism
Nursing Care Plan (NCP) for Hypoparathyroidism
Nursing Care Plan (NCP) for Hypothyroidism
Nursing Care Plan (NCP) for Hypovolemic Shock
Nursing Care Plan (NCP) for Omphalocele
Nursing Care Plan (NCP) for Reye’s Syndrome
Nursing Care Plan (NCP) for Somatic Symptom Disorder (SSD)
Nursing Care Plan (NCP) for Vomiting / Diarrhea
Nursing Care Plan (NCP) for West Nile Virus
Nursing Care Plan for Distributive Shock
Nutrition Assessments
Pituitary Gland
Stomach Cancer (Gastric Cancer)
Vomiting
Adrenal Gland
Advanced Cardiovascular Life Support (ACLS)
Anti-Infective – Antifungals
07.01 CVA (Cerebrovascular Accident/Stroke) for CCRN Review
07.10 Neurologic Review questions for CCRN Review
Acute Confusion
Altered Mental Status Nursing Mnemonic (AEIOU TIPS)
Altered Mental Status- Delirium and Dementia for Progressive Care Certified Nurse (PCCN)
Assessment of Guillain-Barre Syndrome Nursing Mnemonic (GBS=PAID)
Blood Brain Barrier (BBB)
Brain Tumors
Brain Tumors
Cerebral Metabolism
Cerebral Palsy (CP)
Cerebral Perfusion Pressure Case Study (60 min)
Electroencephalography (EEG)
Encephalopathies
Encephalopathy Case Study (45 min)
Head and Spinal Cord Trauma for Certified Emergency Nursing (CEN)
Hydrocephalus
Increased Intracranial Pressure
Impulse Transmission
Increased Intracranial Pressure (ICP) for Certified Emergency Nursing (CEN)
Intracranial Hemorrhage
Intracranial Pressure ICP
Levels of Consciousness (LOC)
Mannitol (Osmitrol) Nursing Considerations
Meningitis
Membrane Potentials
Meningitis Assessment Findings Nursing Mnemonic (FAN LIPS)
Meningitis for Certified Emergency Nursing (CEN)
Migraines
Nerve Transmission
Nervous System Anatomy
Neuro A&P Module Intro
Neuro Anatomy
Neuro Assessment
Neuro Assessment Module Intro
Neuro Course Introduction
Neuro Disorders Module Intro
Neuro Terminology
Neuro Trauma Module Intro
Neurogenic Shock for Certified Emergency Nursing (CEN)
Neurological Disorders (Multiple Sclerosis, Myasthenia Gravis, Guillain-Barré Syndrome) for Certified Emergency Nursing (CEN)
Neurological Fractures
Nursing Care Plan (NCP) for Brain Tumors
Nursing Care Plan (NCP) for Encephalopathy
Nursing Care Plan (NCP) for Meningitis
Nursing Care Plan (NCP) for Migraines
Nursing Care Plan (NCP) for Multiple Sclerosis (MS)
Nursing Care Plan (NCP) for Seizures
Nursing Care Plan (NCP) for Spinal Cord Injury
Nursing Care Plan (NCP) for Stroke (CVA)
Nursing Case Study for Head Injury
Parasympatholytics (Anticholinergics) Nursing Considerations
Parasympathomimetics (Cholinergics) Nursing Considerations
Seizure Causes (Epilepsy, Generalized)
Seizure Disorder for Progressive Care Certified Nurse (PCCN)
Seizure Disorders for Certified Emergency Nursing (CEN)
Seizure Management in the ER
Seizures Case Study (45 min)
Spina Bifida – Neural Tube Defect (NTD)
Spinal Cord Injury
Spinal Cord Injury Case Study (60 min)
Stroke (CVA) Management in the ER
Stroke Assessment (CVA)
Stroke Case Study (45 min)
Stroke Concept Map
Stroke for Certified Emergency Nursing (CEN)
Stroke for Progressive Care Certified Nurse (PCCN)
Stroke Nursing Care (CVA)
Casting & Splinting
Complications of Immobility
Head to Toe Nursing Assessment (Physical Exam)
Health & Stress
Intro to Health Assessment
Introduction to Health Assessment
Joints
Marfan Syndrome
Musculoskeletal Assessment
Musculoskeletal Course Introduction
Musculoskeletal Module Intro
Musculoskeletal Terminology
Nursing Care Plan (NCP) for Abdominal Pain
Nursing Care Plan (NCP) for Activity Intolerance
Nursing Care Plan (NCP) for Cerebral Palsy (CP)
Nursing Care Plan (NCP) for Clubfoot
Nursing Care Plan (NCP) for Lyme Disease
Nursing Care Plan (NCP) for Marfan Syndrome
Nursing Care Plan (NCP) for Neural Tube Defect, Spina Bifida
Nursing Care Plan (NCP) for Osteoporosis
Nursing Care Plan (NCP) for Scoliosis
Nursing Care Plan (NCP) for Spinal Cord Injury
Nursing Care Plan (NCP) for Systemic Lupus Erythematosus (SLE)
Nursing Care Plan for Fibromyalgia
Nursing Care Plan for Scleroderma
Nutrition Assessments
Osteosarcoma
Physiological Changes
Positioning (Pressure Injury Prevention and Tourniquet Safety) for Certified Perioperative Nurse (CNOR)
Report For Transferring To a Higher Level of Care
The SOCK Method – O