Antiviral Agents for Treatment

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Outline

Overview

    1. Antiviral Agents for Protection– Anti-viral medications attack viruses. There are specific antivirals and broad-spectrum antivirals. Their mechanisms do not destroy the virus but instead hinder their development.  
      1. Mechanisms of Antiviral Drug Action
        1. Attachment antagonists- these drugs can help prevent attachment to the host cell and inhibit entry. (HIV targeting helper T cells/Drugs that block CD4 or CCR5 receptors on a helper T cell. example drug: Fuzeon Is an HIV fusion inhibitor)
        2. Inhibition of viral uncoating- Drugs that prevent viruses carryout the process known as uncoating, where they expell their genome from their capsid during or after penetration. ex. Amantidine inhibit uncoating of the influenzae virus.
        3. Inhibition of nucleic acid synthesis- inhibit the production fo DNA or RNA. ex. Acyclovir- used to treat herpes simplex and varicella zoster.
        4. Inhibition of protein synthesis- All viruses use the cellular ribosomes to translate their viral mRNA then translate that into structural and envelope proteins as well as viral enzymes.
        5. Inhibition of viral proteins- Compromising the envelope or structure of a viral enzyme can stop it from infecting other cells. One example is the enzyme Integrase which is used to combine viral genome to host DNA. ex. Raltegravir inhibits integrase and is used to treat HIV infection.
      2. Antivirals are not used for bacterial infections. Just as antibiotics do not treat viral infections, so is the case with antiviral drugs not effective against bacterial infections.

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Transcript

Today we’re going to be talking about Antiviral Agents for protection.

In this lesson on antiviral agents for protections we will discuss exactly what an antiviral agent is and explains what it can and cannot do as well as  discuss how they work.

 

An antiviral agent is something that can target specific viruses are these agents can be broad spectrum and affect many types of viruses. These antiviral agents do NOT destroy viruses but instead they hinder their development. So pictured here is a capsule of one of the most famous antiviral agents commonly known as Tamiflu. This drug targets influenza and the active ingredient was isolated in the Chinese anise star plant.  And if given within 24-48 hours of flu symptoms and testing positive this drug will prevent the virus from being released from our cells to then go and infect other cells.

That is one method of antiviral drug actions. Other ways include acting as  antagonists that prevent viruses from entering into our cells. (a mechanism by the drug Fuzeion for treating HIV)

Actually inhibiting viral uncoating so that they cannot release their viral DNA or RNA which is the method of Amantadine which can target Influenza A.  Herpes and Chicken Pox can be attacked with a drug named Acyclovar which inhibits the virus from synthesis its nucleic acids (DNA/RNA).  Another mechanism block the production of viral proteins which renders them helpless and lastly some antivirals can actual inhibit viral proteins themselves, like the enzyme protein integrase that when inhibited prevents viral DNA combining with host DNA.

So one final thought about antivirals we can remember by this quote from Benjamin Franklin. that state the best doctor gives the least medicines.

Antivirals do not treat bacterial infections. So it is important to only use these drugs once it is determined the patient tests positive for the virus.

 

So in review Antivirals DO NOT destroy viruses. Antivirals do hinder the development of viruses. And this is done as antivirals inhibit viral processes. And lastly antivirals DO not treat bacterial infections.

We love you guys! Go out and be your best self today! And as always, Happy Nursing!

 

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Concepts Covered:

  • EENT Disorders
  • Oncology Disorders
  • Microbiology
  • Emergency Care of the Cardiac Patient
  • Vascular Disorders
  • Cardiac Disorders
  • Central Nervous System Disorders – Brain
  • Medication Administration
  • Labor Complications
  • Intraoperative Nursing
  • Musculoskeletal Trauma
  • Respiratory Disorders
  • Shock
  • Infectious Respiratory Disorder
  • Disorders of Pancreas
  • Pregnancy Risks
  • Male Reproductive Disorders
  • Adult
  • Basics of Chemistry
  • Emergency Care of the Respiratory Patient
  • Neonatal
  • Newborn Care
  • Hematologic Disorders
  • Cardiovascular Disorders
  • Sexually Transmitted Infections
  • Nervous System
  • Terminology
  • Disorders of the Thyroid & Parathyroid Glands
  • Learning Pharmacology
  • Integumentary Disorders
  • EENT Disorders
  • Liver & Gallbladder Disorders
  • Prenatal Concepts
  • Postpartum Complications
  • Labor and Delivery
  • Dosage Calculations
  • Concepts of Pharmacology
  • Depressive Disorders
  • Bipolar Disorders
  • Anxiety Disorders
  • Cognitive Disorders
  • Personality Disorders
  • Noninfectious Respiratory Disorder
  • Disorders of the Posterior Pituitary Gland
  • Upper GI Disorders
  • Urinary Disorders
  • Substance Abuse Disorders
  • Urinary System
  • Immunological Disorders
  • Prefixes
  • Suffixes
  • Test Taking Strategies

Study Plan Lessons

Acetaminophen (Tylenol) Nursing Considerations
Antineoplastics
Fungal Infections
Antiviral Agents for Treatment
Basics of Microbial Control
Pediatric Dosage Calculations
Hypertension (HTN) Concept Map
Coronary Artery Disease Concept Map
Interactive Practice Drip Calculations
Tension and Cluster Headaches
Migraines
Patient Controlled Analgesia (PCA)
Epidural
Anesthetic Agents
Barbiturates
Opioids
Bronchodilators
Anti-Infective – Glycopeptide
Anti-Infective – Antitubercular
Antidiabetic Agents
Anticonvulsants
Thrombolytics
Anti-Infective – Lincosamide
Anti-Infective – Antivirals
Anti-Infective – Antifungals
Anti-Infective – Sulfonamides
Anti-Infective – Fluoroquinolones
Anti-Infective – Macrolides
Anti-Infective – Carbapenems
Anti-Infective – Aminoglycosides
ACLS (Advanced cardiac life support) Drugs
Anesthetic Agents
Viruses & Fungi
Nuclear Chemistry
Rapid Sequence Intubation
CRNA
Bronchodilators
Anticonvulsants
Cardiopulmonary Arrest
Anti-Infective – Glycopeptide
Antidiabetic Agents
Bacteria
Nuclear Chemistry
Neonatal Resuscitation Program (NRP)
Thrombolytics
Anti-Infective – Lincosamide
Barbiturates
Prostaglandins in Pregnancy
Eye Prophylaxis for Newborn
Phytonadione (Vitamin K) for Newborn
Thrombin Inhibitors
Anti-Infective – Antitubercular
Chemical Equations
Chemical Bonds & Compounds
Betamethasone and Dexamethasone in Pregnancy
Sedatives-Hypnotics
Tocolytics
Sympatholytics (Alpha & Beta Blockers)
Opioids
Coumarins
Anti-Platelet Aggregate
Properties of Matter
Scientific Notation & Measurement
Chemical Reactions
Anti-Infective – Antivirals
Anti-Infective – Antifungals
Anti-Infective – Tetracyclines
Anti-Infective – Sulfonamides
Anti-Infective – Fluoroquinolones
Anti-Infective – Macrolides
Anti-Infective – Carbapenems
Anti-Infective – Aminoglycosides
Parasympathomimetics (Cholinergics) Nursing Considerations
Sympathomimetics (Alpha (Clonodine) & Beta (Albuterol) Agonists)
ACLS (Advanced cardiac life support) Drugs
Psychiatry Terminology
Pharmacology Terminology
Nursing Care and Pathophysiology for Hashimoto’s Thyroiditis
The SOCK Method – Overview
The SOCK Method – O
The SOCK Method – C
The SOCK Method – K
The SOCK Method – S
Hanging an IV Piggyback
Spiking & Priming IV Bags
IV Push Medications
IM Injections
SubQ Injections
Insulin Mixing
Medications in Ampules
Drawing Up Meds
Topical Medications
EENT Medications
Pill Crushing & Cutting
NG Tube Med Administration (Nasogastric)
Hb (Hepatitis) Vaccine
Phytonadione (Vitamin K)
Eye Prophylaxis for Newborn (Erythromycin)
Lung Surfactant
Rh Immune Globulin (Rhogam)
Meds for PPH (postpartum hemorrhage)
Uterine Stimulants (Oxytocin, Pitocin)
Prostaglandins
Opioid Analgesics
Magnesium Sulfate
Betamethasone and Dexamethasone
Tocolytics
Complex Calculations (Dosage Calculations/Med Math)
IV Infusions (Solutions)
Injectable Medications
Oral Medications
Dimensional Analysis Nursing (Dosage Calculations/Med Math)
Basics of Calculations
Pharmacokinetics
Pharmacodynamics
Antidepressants
Mood Stabilizers
Antianxiety Meds
Meds for Alzheimers
Sedatives-Hypnotics
Antipsychotics
Heart (Cardiac) Failure Therapeutic Management
NG Tube Medication Administration
Disease Specific Medications
Vasopressin
TCAs
SSRIs
Proton Pump Inhibitors
Anti-Infective – Penicillins and Cephalosporins
Parasympatholytics (Anticholinergics) Nursing Considerations
NSAIDs
Nitro Compounds
MAOIs
Magnesium Sulfate
Insulin
HMG-CoA Reductase Inhibitors (Statins)
Hydralazine
Histamine 2 Receptor Blockers
Histamine 1 Receptor Blockers
Epoetin Alfa
Diuretics (Loop, Potassium Sparing, Thiazide, Furosemide/Lasix)
Corticosteroids
Cardiac Glycosides
Calcium Channel Blockers
Benzodiazepines
Autonomic Nervous System (ANS)
Atypical Antipsychotics
Angiotensin Receptor Blockers
ACE (angiotensin-converting enzyme) Inhibitors
Renin Angiotensin Aldosterone System
6 Rights of Medication Administration
Essential NCLEX Meds by Class
Therapeutic Drug Levels (Digoxin, Lithium, Theophylline, Phenytoin)
54 Common Medication Prefixes and Suffixes
12 Points to Answering Pharmacology Questions