Magnesium Sulfate in Pregnancy

Pharmacology for Nursing (MedMaster)

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Outline

Overview

Used as an anticonvulsant in the pregnant patient
1. Decreases risk of preeclampsia from turning into eclampsia
Has been used as a tocolytic, but research shows there are other more effective options
May suppress uterine contractions in the laboring patient

Nursing Points

General

If given in an actively seizing patient, it is an emergency.
1. IV bolus given
2. IM injections
3. Then continuous IV infusion.
Given in a preeclamptic patient to prevent seizure
1. May be continued up to 24 hours postpartum

Assessment

Closely monitor mag levels
1. Normal serum mag level is 1.5-2.5 mEq/L
2. Target therapeutic range for this indication is 2.5-7.5 mEq/L
3. Mag over 12 mEq/L can be fatal
Closely monitor vitals per protocol/order set
1. Hypotension
Closely monitor deep tendon reflexes, respiratory function, heart monitor
1. Patellar reflex = legs hanging over bed, use reflex hammer to hit the quadricep tendon, do it on both legs and rate. Suppressed reflex can be a sign of impending respiratory arrest!
  1. 0 – no response
  2. 1 – sluggish
  3. 2 – normal
  4. 3 – more brisk, slightly hyperactive
  5. 4 – brisk, hyperactive
2. Call if RR is less than 12/min
3. Check RR + reflex before IV doses. Reflex MUST be present and RR greater than 16 before each IV dose (unless hospital policy reflects otherwise).
Watch renal function on BMP or CMP and urinary output (med eliminated by kidneys

Therapeutic Management

Titrating magnesium based on assessment findings
Calcium gluconate easily accessible
1. Antidote for Magsulfate

Nursing Concepts

Pharmacology
Lab values
Safety

Patient Education

Side effects

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Pharmacology for Nursing (MedMaster)

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Magnesium Sulfate in Pregnancy

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Included In This Lesson

Study Tools For Magnesium Sulfate in Pregnancy

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Outline

Overview

Nursing Points

General

Assessment

Therapeutic Management

Nursing Concepts

Patient Education

View the FULL Outline

Pharmacology for Nursing (MedMaster)

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