Anti-Infective – Fluoroquinolones
Included In This Lesson
Outline
Overview
- Overview
- Bacterial agents
- Types
- Norfloxacin (Noroxin)
- Ciprofloxacin (Cipro)
- Levofloxacin (Levaquin)
- Moxifloxacin (Avelox)
- Gatifloxacin (Tequin)
- Gemifloxacin (Factive)
- Mechanism of Action
- Destroy bacteria by altering their DNA
- Kill gram – / gram + organisms
- Indications
- Urinary tract infections
- Respiratory infections / Pneumonia
- Sexually transmitted infections (STIs)
- Bone and joint infections
- Prostate infections
- Contraindications
- Drug allergy
- Cardiac function
- Dysrhythmias
- Interactions
- Antacids
- Iron
- Zinc preparations
- Sucralfate
- Magnesium / Calcium
- Oral anticoagulants
Transcript
Hey there, and today’s we are going to discuss fluoroquinolones, which are a certain type of antibiotic class.
Alright, let’s review. Fluoroquinolones are bactericidal, meaning that these antibiotics KILL bacteria. They don’t simply suppress bacterial reproduction.
Fluoroquinolones all end in -FLOXACIN, which is an easy way to remember this drug class.
The mechanism of action that causes these antibiotics to work is related to their ability to alter bacterial DNA. Fluoroquinolones are used to treat gram +/- organisms.
Indications for fluoroquinolones include urinary tract infections, respiratory infections, sexually transmitted infections, bone/joint infections and prostate infections. The top three indications can be remember by URS.
Contraindications for fluoroquinolones include drug allergy and cardiac dysrhythmias. If your patient has a past medical history of ventricular tachycardia, for example, this drug wouldn’t be a good choice. Any cardiac dysrhythmia history would be a concern regarding this antibiotic use.
Some other medications that can Interact with fluoroquinolones include sucralfate, antacids, iron, magnesium, calcium, oral anticoagulants and zinc preparations. An easy way to remember these is SAIMOZ.
Psychiatric side effects for fluoroquinolones include depression and anxiety.
Sensation and muscle side effects for fluoroquinolones include sensation changes and swelling, pain and tendon rupture. There isn’t a definitive reason, researchers speculate it can be linked to mitochondrial damage, likely oxidative stress.
Cardiovascular side effects for fluoroquinolones include aortic tear and rupture. Signs and symptoms include sudden, severe chest pain, hypotension, flank or back pain. These patients often die before they are able to seek surgical intervention.
Endocrine side effects for fluoroquinolones include hypoglycemia. If your patient has a baseline of hypoglycemia, this will exacerbate their condition.
Priority nursing concepts for fluoroquinolones include pharmacology and infection control.
Alright let’s review fluoroquinolones. These antibiotics end in -FLOXACIN. Top three indications can be remembered by URS (urine, respiratory and sexual transmitted infections). Contraindications include drug allergies and cardiac dysrhythmias. This drug class has many interactions, which can be remembered by SAIMOZ (sucralfate, antacids, iron, magnesium/calcium, oral anticoagulants and zinc preparations). Lastly side effects include – depression and anxiety / sensation changes and swelling, pain and tendon rupture / aortic tear and rupture / hypoglycemia.
You know now the important details regarding fluoroquinolones. Now, go out and be your best self today and as always, Happy Nursing!
KRISTELLE
Concepts Covered:
- Cardiac Disorders
- Cardiovascular
- Circulatory System
- Nervous System
- Skeletal System
- Emergency Care of the Cardiac Patient
- Shock
- Shock
- Disorders of the Posterior Pituitary Gland
- Endocrine
- Disorders of Pancreas
- Hematology
- Gastrointestinal
- Upper GI Disorders
- Liver & Gallbladder Disorders
- Newborn Complications
- Renal
- Respiratory
- Test Taking Strategies
- Note Taking
- Prefixes
- Suffixes
- Medication Administration
- Gastrointestinal Disorders
- Respiratory Disorders
- Respiratory System
- Urinary System
- Pregnancy Risks
- Labor Complications
- Hematologic Disorders
- Fundamentals of Emergency Nursing
- Factors Influencing Community Health
- Delegation
- Perioperative Nursing Roles
- Lower GI Disorders
- Emergency Care of the Neurological Patient
- Acute & Chronic Renal Disorders
- EENT Disorders
- Central Nervous System Disorders – Brain
- Documentation and Communication
- Preoperative Nursing
- Disorders of the Adrenal Gland
- Disorders of the Thyroid & Parathyroid Glands
- Endocrine System
- Legal and Ethical Issues
- Adult
- Basics of NCLEX
- Communication
- Understanding Society
- Immunological Disorders
- Substance Abuse Disorders
- Studying
- Fetal Development
- Terminology
- Cognitive Disorders
- Musculoskeletal Trauma
- Intraoperative Nursing
- Tissues and Glands
- Vascular Disorders
- Eating Disorders
- Microbiology
- Male Reproductive Disorders
- Sexually Transmitted Infections
- Infectious Respiratory Disorder
- Anxiety Disorders
- Depressive Disorders
- Oncology Disorders
- Personality Disorders
- Psychotic Disorders
- Trauma-Stress Disorders
- Respiratory Emergencies
- Noninfectious Respiratory Disorder
- Basics of Chemistry
- Neurologic and Cognitive Disorders
- Integumentary Disorders
- Newborn Care
- Basics of Mathematics
- Statistics
- Emergency Care of the Trauma Patient
- Hematologic System
- Hematologic Disorders
- Developmental Considerations
- Digestive System
- Behavior
- Postpartum Care
- Basic
- Integumentary Disorders
- Metabolism
- Cardiovascular Disorders
- Concepts of Population Health
- Musculoskeletal Disorders
- EENT Disorders
- Basics of Human Biology
- Postoperative Nursing
- Urinary Disorders
- Neurological Emergencies
- Prenatal Concepts
- Disorders of Thermoregulation
- Community Health Overview
- Neurological Trauma
- Renal Disorders
- Concepts of Mental Health
- Childhood Growth and Development
- Prenatal and Neonatal Growth and Development
- Postpartum Complications
- Concepts of Pharmacology
- Integumentary Important Points
- Emotions and Motivation
- Health & Stress
- Multisystem
- Proteins
- Renal and Urinary Disorders
- Developmental Theories
- Reproductive System
- Endocrine and Metabolic Disorders
- Musculoskeletal Disorders
- Adulthood Growth and Development
- Psychological Emergencies
- Growth & Development
- Female Reproductive Disorders
- Basics of Sociology
- Neurological
- Intelligence and Language
- Labor and Delivery
- Reading
- Oncologic Disorders
- Bipolar Disorders
- Med Term Basic
- Peripheral Nervous System Disorders
- Infectious Disease Disorders
- Muscular System
- Central Nervous System Disorders – Spinal Cord
- Learning Pharmacology
- Prioritization
- Somatoform Disorders
- Writing
- Pediatric
- Emergency Care of the Respiratory Patient
- Sensory System
- State of Consciousness