HELLP Syndrome

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HELLP Syndrome Pathochart (Cheatsheet)
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Outline

Overview

  1.  HELLP
    1. Life threatening
    2. Requires emergent delivery

Nursing Points

General

  1. HELLP
    1. Hemolysis
    2. Elevated Liver enzymes
    3. Low Platelets
  2. At risk
    1. Older
    2. Multiparity

Assessment

  1. Labwork will show:
    1. Low RBC
    2. Elevated liver enzymes (AST, ALT)
    3. Low platelets
    4. Do NOT need all 3 to be diagnosed with HELLP!
    5. Watch lab trends
  2. Petechiae
    1. Low platelets
  3. Dizziness
    1. Hemolytic anemia
  4. Tachycardia
    1. Hemolytic anemia
  5. Nausea, vomiting
    1. Elevated liver enzymes
  6. Observe for DIC –> Patients are at risk
  7. Quick assessment and diagnosis is necessary, death can occur if not discovered

Therapeutic Management

  1. Attempt to stabilize
    1. Magnesium Sulfate
    2. Antihypertensives
    3. IV fluids
      1. Caution because of fluid overload risk
    4. Monitoring
  2. Delivery
    1. The only cure
    2. Emergent
  3. The syndrome should resolve 24-48 hours after delivery

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Transcript

Today we’re going to be talking about HELLP Syndrome.

 

In this lesson on HELLP syndrome we will cover what it is, what to look for, and treatment for this patient. 


Before we really dive in, it is important to know that this is a syndrome just in pregnancy. A patient is going to be more at risk if they are older, older than 34, or carrying multiple or multiparity. Some believe this is an exacerbation of preeclampsia and others believe it to be its own issue. Preeclampsia does occur a lot in these women or they show some symptoms of preeclampsia with HELLP symptoms. Refer to the lesson on preeclampsia to understand more about that disease process.

 

So let’s look at lab work. HELLP is actually a mnemonic so it makes it easy to remember. It is hemolysis, elevated liver enzymes, and low platelets. Now something super important that I want you to all to make sure you remember is that you do NOT need to have all 3 of these to be considered in HELLP syndrome. If you have all 3 you are in bad shape but you can have 1 of them that continues to trend down and still be diagnosed with HELLP. Next let’s look at some symptoms. 

 

Alright here are some symptoms. We have petechiae because we have low platelets. Abdominal pain and nausea/vomitting is because the liver enzymes are elevated and that liver is swollen. Tachycardia and dizziness because we have hemolysis of RBCs. So the patient is anemic. And usually these patients are also hypertensive. Remember when I said that some believe its an exacerbation of preeclampsia which is a hypertensive disorder of pregnancy. So you most likely will see that too. Alright now, what will we do to treat these patients?

 

Ok guys, delivery is the ONLY cure. These moms are very sick and a very sick mom can not grow a very healthy baby. If HELLP is left untreated these women can die. And Ill tell you, I’ve seen it. So it doesn’t matter if the baby is not to viability yet, if that mother is getting sicker and sicker than a delivery needs to happen. At this point, it is better to have 1 patient live than 2 die. Symptoms should resolve within 24-48 hours of delivery. Now if the mother comes in and is showing mild symptoms they will first attempt to stabilize. So medications. We can give mag sulfate as seizure prevention and other antihypertensives. She can be given blood products. We can give IV fluids to hydrate but be cautious in a hypertensive, fluid overloaded individual, right? Labs will be monitored to see if stabilization has occurred. If labs are still shifting in the wrong direction then delivery needs to happen.

 

So let’s wrap this up. HELLP stands for hemolysis, elevated liver enzymes, and low platelets. Remember this patient might present with anemia symptoms like tachycardia and dizziness. The patient might have epigastric pain, nausea from that inflamed liver, and petechiae from low platelets. Treatment to stabilize is mag sulfate if we need to prevent seizures and antihypertensives which are usually labetalol or hydralazine and possibly fluids to hydrate, but we have to be careful because they might be hypertensive and already in fluid overload. And our only cure is to deliver. Remember these patients are very sick and might seem stable but can quickly turn.


We love you guys! Go out and be your best self today! And as always, Happy Nursing!

 

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OB (Maternal Newborn)

The OB (Obstetrics) or Maternal Newborn Course breaks down the most important things you need to know to care for a client before, during, and after pregnancy. Every aspect is broken down into manageable chunks to eliminate confusion and overwhelm. We help you understand what common risks and complications are, how the baby grows and develops, and how to assess both mom and baby after the baby is born. We even talk about medications that are commonly given during pregnancy.

Course Lessons

OB Course Introduction
OB Course Introduction
Maternity Nursing
Menstrual Cycle
Family Planning & Contraception
OB Assessment
Gestation & Nägele’s Rule: Estimating Due Dates
Gravidity and Parity (G&Ps, GTPAL)
Signs of Pregnancy (Presumptive, Probable, Positive)
Fundal Height Assessment for Nurses
Maternal Risk Factors
Prenatal Period
Physiological Changes
Discomforts of Pregnancy
Antepartum Testing
Nutrition in Pregnancy
Risk Conditions Of Pregnancy
Abortion in Nursing: Spontaneous, Induced, and Missed
Anemia in Pregnancy
Cardiac (Heart) Disease in Pregnancy
Chorioamnionitis
Gestational Diabetes (GDM)
Disseminated Intravascular Coagulation (DIC)
Ectopic Pregnancy
Hematomas in OB Nursing: Causes, Symptoms, and Nursing Care
Hydatidiform Mole (Molar pregnancy)
Hyperemesis Gravidarum
Gestational HTN (Hypertension)
Incompetent Cervix
Infections in Pregnancy
Preeclampsia: Signs, Symptoms, Nursing Care, and Magnesium Sulfate
HELLP Syndrome
Fetal Development
Fertilization and Implantation
Fetal Development
Fetal Environment
Fetal Circulation
Labor And Delivery
Process of Labor
Mechanisms of Labor
Leopold Maneuvers
Fetal Heart Monitoring (FHM)
Obstetrical Procedures
Labor And Delivery Complications
Premature Rupture of the Membranes (PROM)
Prolapsed Umbilical Cord
Placenta Previa
Abruptio Placentae (Placental abruption)
Preterm Labor
Precipitous Labor
Dystocia
Postpartum Care
Postpartum Physiological Maternal Changes
Postpartum Interventions
Postpartum Discomforts
Breastfeeding
Postpartum Complications
Postpartum Hematoma
Postpartum Hemorrhage (PPH)
Mastitis
Subinvolution
Postpartum Thrombophlebitis
Newborn Care
Initial Care of the Newborn (APGAR)
Newborn Physical Exam
Body System Assessments
Newborn Reflexes
Newborn Complications
Babies by Term
Meconium Aspiration
Transient Tachypnea of Newborn
Retinopathy of Prematurity (ROP)
Hyperbilirubinemia (Jaundice)
Erythroblastosis Fetalis
Addicted Newborn
Fetal Alcohol Syndrome (FAS)
Newborn of HIV+ Mother
Maternal And Newborn Pharmacology
Tocolytics
Betamethasone and Dexamethasone
Magnesium Sulfate
Opioid Analgesics
Prostaglandins
Uterine Stimulants (Oxytocin, Pitocin)
Meds for PPH (postpartum hemorrhage)
Rh Immune Globulin (Rhogam)
Lung Surfactant
Eye Prophylaxis for Newborn (Erythromycin)
Phytonadione (Vitamin K)
Hb (Hepatitis) Vaccine