Sedatives-Hypnotics

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140 Must Know Meds (Book)
Zolpidem (Ambien) (Picmonic)
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Outline

Overview

  1. CNS depressants used for insomnia, anxiety, apprehension. Should only be used for short-term therapy.
  2. May also be used for sedation/anesthesia

Nursing Points

Nursing Considerations

  1. Use lowest dose necessary to achieve desired effects
  2. Use extreme caution if patient has a history of substance abuse (does benefit outweigh risk?)
  3. Avoid driving, ETOH
  4. Use caution in patients at risk for suicide
  5. For sleep
    1. Take approximately 30 min before desired effect
    2. Ensure patient has a full 8 hours available to sleep
    3. May continue to feel effects after awakening
    4. Diprivan – prevents REM sleep
  6. Tolerance may develop; use caution
    1. Require higher and higher doses
  7. Watch for overdose, withdrawal
  8. Should taper down; don’t abruptly D/C

Examples

  1. Barbiturates
    1. Phenobarbital
    2. Pentobarbital
  2. Anesthetic
    1. Diprivan
  3. NMDA Antagonist
    1. Ketamine

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Transcript

In this lesson we’re going to cover the important points for medications known as sedatives or hypnotics.

These medications are central nervous system depressants that are usually used for insomnia anxiety or anesthesia and are usually considered short-term medications. Examples are barbiturates like phenobarbital or pentobarbital, diprivan also known as propofol, and ketamine. Each of these is a different chemical drug class but they tend to have the same effect on patients so we’re going to cover some general nursing considerations for all of them and I’ll give a few specific points

Anytime you’re using a sedative you always want to use the lowest dose necessary to achieve your desired results. This is kind of like a form of titration. If you can achieve appropriate sleep or sedation with a dose of 2 mg for example, there’s no need to increase that dose to 5 mg. With medications like these we always want to use caution in any client with a history of substance abuse or suicidal behavior because of the risk for misuse and the dangerous effects that can have. Obviously these medications have a sedative effect so client should be cautious or simply not use this medication at the same time as drinking alcohol. They should also make sure that they know how their dose affects them before they start driving. Similar to most of our mental health medications it’s important that we taper these down slowly when it is time to stop because there’s a risk for withdrawal symptoms. And of course there’s always a risk for overdose or toxicity so make sure that you’re watching your client closely and assessing their level of consciousness and their ability to protect their own airway, which is usually the number one killer in an overdose of medications like these.

Some of these medications are used for insomnia, so it’s important that we educate our patients on appropriate use to help them sleep. They should be taking the medication about 30 minutes before they want to be asleep to give it a chance to work. they should also make sure that they have a full 8 hours available to sleep. These medications should not be used for quick cat naps in the afternoon. Now, even if they sleep for a full 9 or 10 hours, patients may still feel some of the effects of the medication when they wake up in the morning. Almost like a hangover. Now I bet you’re wondering why there’s a picture of Michael Jackson on this slide. In the last 2 months of his life Michael Jackson struggled with insomnia severely and was actually being dosed with diprivan or propofol to help him sleep. here’s the thing about Propofol… I personally had propofol during an endoscopy once after I had been awake all night at a night shift. they gave me propofol for the procedure and I was only out for maybe 15 minutes, but I felt like I had had a full night’s sleep when I woke up. The problem was that within an hour or so I was exhausted again because it wasn’t true sleep. Propofol actually prevents you from achieving rapid eye movement or REM sleep which is the most restorative form of sleep. So some experts have said that Michael Jackson went nearly two months without REM sleep and that even if he hadn’t unfortunately been overdosed with Propofol that the lack of sleep might have killed him anyway. So it’s important to understand that these medications are not for long-term solutions they are only for short term help. This is especially true because patients can develop a tolerance to the medications and require higher and higher doses for the same effect. So if you see someone who’s on one of these medications for an extended period of time, you need to advocate for them to be on a more long-term medication.

So remember that sedatives and hypnotics are central nervous system depressant used for insomnia anxiety and anesthesia for short-term Solutions. It’s always important to weigh the risks versus benefits. we want to be cautious in the elderly who might react stronger to the same dose or those using alcohol because of the interaction. We also want to be extremely cautious in those with history of substance abuse or suicidal Behavior because of the risk of misuse of these medications. We always want to keep safety first because of those sedative effects they would be at risk for Falls they need to be cautious before they drive and of course we need to watch their Airway in the case of overdose or oversedation. And again always just consider your dosing make sure you’re using the least dose possible to get the desired result watch for overdose withdrawal and tolerance and advocate for more long-term medications if necessary.

So those are the important points for sedatives and hypnotics. Make sure you check out all the resources attached to this lesson. Now, go out and be your best selves today. And, as always, happy nursing!!

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Pharmacology

Concepts Covered:

  • Concepts of Pharmacology
  • Test Taking Strategies
  • Prefixes
  • Suffixes
  • Bipolar Disorders
  • Immunological Disorders
  • Medication Administration
  • Learning Pharmacology
  • Dosage Calculations
  • Noninfectious Respiratory Disorder
  • Anxiety Disorders
  • Substance Abuse Disorders
  • Adult
  • Cardiac Disorders
  • Cardiovascular Disorders
  • Hematologic Disorders
  • Central Nervous System Disorders – Brain
  • Depressive Disorders
  • Disorders of Pancreas
  • Liver & Gallbladder Disorders
  • Upper GI Disorders
  • Urinary System
  • Pregnancy Risks
  • Microbiology
  • Infectious Respiratory Disorder
  • Respiratory Disorders
  • Shock
  • Male Reproductive Disorders
  • Sexually Transmitted Infections
  • Personality Disorders
  • Psychotic Disorders
  • Nervous System
  • Labor Complications
  • Postpartum Complications
  • Prenatal Concepts
  • Newborn Care
  • Musculoskeletal Trauma
  • Intraoperative Nursing
  • Vascular Disorders
  • Disorders of the Posterior Pituitary Gland
  • Oncology Disorders
  • EENT Disorders
  • Emergency Care of the Cardiac Patient
  • Female Reproductive Disorders
  • Gastrointestinal Disorders
  • Lower GI Disorders
  • Neurologic and Cognitive Disorders
  • Acute & Chronic Renal Disorders
  • Urinary Disorders
  • Disorders of the Adrenal Gland
  • Integumentary Disorders
  • Neurological
  • Postoperative Nursing
  • Peripheral Nervous System Disorders
  • Disorders of the Thyroid & Parathyroid Glands
  • Cardiovascular

Study Plan Lessons

Pharmacology Course Introduction
12 Points to Answering Pharmacology Questions
54 Common Medication Prefixes and Suffixes
Therapeutic Drug Levels (Digoxin, Lithium, Theophylline, Phenytoin)
Essential NCLEX Meds by Class
6 Rights of Medication Administration
Pharmacodynamics
Pharmacokinetics
The SOCK Method – Overview
The SOCK Method – S
The SOCK Method – O
The SOCK Method – C
The SOCK Method – K
Basics of Calculations
Oral Medications
Injectable Medications
IV Infusions (Solutions)
Complex Calculations (Dosage Calculations/Med Math)
Interactive Pharmacology Practice
Interactive Practice Drip Calculations
Pediatric Dosage Calculations
Disease Specific Medications
Antianxiety Meds
Benzodiazepines
ACLS (Advanced cardiac life support) Drugs
Anti-Platelet Aggregate
NG Tube Medication Administration
Coumarins
Thrombin Inhibitors
Thrombolytics
Anticonvulsants
Antidepressants
MAOIs
SSRIs
TCAs
Antidiabetic Agents
Insulin
Insulin – Mixtures (70/30)
Histamine 1 Receptor Blockers
Histamine 2 Receptor Blockers
Renin Angiotensin Aldosterone System
Sympatholytics (Alpha & Beta Blockers)
ACE (angiotensin-converting enzyme) Inhibitors
Angiotensin Receptor Blockers
Calcium Channel Blockers
Cardiac Glycosides
Anti-Infective – Aminoglycosides
Anti-Infective – Antifungals
Anti-Infective – Antitubercular
Anti-Infective – Antivirals
Anti-Infective – Carbapenems
Anti-Infective – Fluoroquinolones
Anti-Infective – Glycopeptide
Anti-Infective – Lincosamide
Anti-Infective – Macrolides
Anti-Infective – Penicillins and Cephalosporins
Anti-Infective – Sulfonamides
Anti-Infective – Tetracyclines
Atypical Antipsychotics
Antipsychotics
Autonomic Nervous System (ANS)
Sympathomimetics (Alpha (Clonodine) & Beta (Albuterol) Agonists)
Bronchodilators
Diuretics (Loop, Potassium Sparing, Thiazide, Furosemide/Lasix)
Proton Pump Inhibitors
Epoetin Alfa
HMG-CoA Reductase Inhibitors (Statins)
Magnesium Sulfate
Mood Stabilizers
NSAIDs
Tocolytics
Meds for Postpartum Hemorrhage (PPH)
Prostaglandins in Pregnancy
Rh Immune Globulin in Pregnancy
Lung Surfactant for Newborns
Eye Prophylaxis for Newborn
Phytonadione (Vitamin K) for Newborn
Opioids
Opioid Analgesics in Pregnancy
Sedatives-Hypnotics
Barbiturates
Anesthetic Agents
Corticosteroids
Betamethasone and Dexamethasone in Pregnancy
Hydralazine
Nitro Compounds
Vasopressin
ACLS (Advanced cardiac life support) Drugs
Anti-Infective – Aminoglycosides
Anti-Infective – Carbapenems
Anti-Infective – Macrolides
Anti-Infective – Fluoroquinolones
Anti-Infective – Sulfonamides
Anti-Infective – Tetracyclines
Anti-Infective – Antifungals
Anti-Infective – Antivirals
Anti-Infective – Lincosamide
Thrombolytics
Anticonvulsants
Antidiabetic Agents
Sympatholytics (Alpha & Beta Blockers)
Anti-Infective – Antitubercular
Anti-Infective – Glycopeptide
Bronchodilators
Opioids
Barbiturates
Anesthetic Agents
Antineoplastics
Alkylating Agents
Antimetabolites
Anti Tumor Antibiotics
Plant Alkaloids Topoisomerase and Mitotic Inhibitors
Patient Controlled Analgesia (PCA)
Epidural
Insulin Drips
Acetaminophen (Tylenol) Nursing Considerations
Acyclovir (Zovirax) Nursing Considerations
Adenosine (Adenocard) Nursing Considerations
Albuterol (Ventolin) Nursing Considerations
Alendronate (Fosamax) Nursing Considerations
Alprazolam (Xanax) Nursing Considerations
Alteplase (tPA, Activase) Nursing Considerations
Amiodarone (Pacerone) Nursing Considerations
Amitriptyline (Elavil) Nursing Considerations
Amlodipine (Norvasc) Nursing Considerations
Amoxicillin (Amoxil) Nursing Considerations
Ampicillin (Omnipen) Nursing Considerations
ASA (Aspirin) Nursing Considerations
Atenolol (Tenormin) Nursing Considerations
Atorvastatin (Lipitor) Nursing Considerations
Atropine (Atropen) Nursing Considerations
Azithromycin (Zithromax) Nursing Considerations
Benztropine (Cogentin) Nursing Considerations
Bisacodyl (Dulcolax) Nursing Considerations
Bismuth Subsalicylate (Pepto-Bismol) Nursing Considerations
Bupropion (Wellbutrin) Nursing Considerations
Buspirone (Buspar) Nursing Considerations
Butorphanol (Stadol) Nursing Considerations
Calcium Acetate (PhosLo) Nursing Considerations
Calcium Carbonate (Tums) Nursing Considerations
Captopril (Capoten) Nursing Considerations
Carbamazepine (Tegretol) Nursing Considerations
Carbidopa-Levodopa (Sinemet) Nursing Considerations
Cefaclor (Ceclor) Nursing Considerations
Cefdinir (Omnicef) Nursing Considerations
Celecoxib (Celebrex) Nursing Considerations
Cephalexin (Keflex) Nursing Considerations
Chlorpromazine (Thorazine) Nursing Considerations
Cimetidine (Tagamet) Nursing Considerations
Ciprofloxacin (Cipro) Nursing Considerations
Clindamycin (Cleocin) Nursing Considerations
Clopidogrel (Plavix) Nursing Considerations
Codeine (Paveral) Nursing Considerations
Cortisone (Cortone) Nursing Considerations
Cyclosporine (Sandimmune) Nursing Considerations
Dexamethasone (Decadron) Nursing Considerations
Diazepam (Valium) Nursing Considerations
Digoxin (Lanoxin) Nursing Considerations
Diltiazem (Cardizem) Nursing Considerations
Dimensional Analysis Nursing (Dosage Calculations/Med Math)
Diphenhydramine (Benadryl) Nursing Considerations
Diphenoxylate-Atropine (Lomotil) Nursing Considerations
Divalproex (Depakote) Nursing Considerations
Dobutamine (Dobutrex) Nursing Considerations
Dopamine (Inotropin) Nursing Considerations
Enalapril (Vasotec) Nursing Considerations
Enoxaparin (Lovenox) Nursing Considerations
Epinephrine (EpiPen) Nursing Considerations
Epoetin (Epogen) Nursing Considerations
Erythromycin (Erythrocin) Nursing Considerations
Escitalopram (Lexapro) Nursing Considerations
Famotidine (Pepcid) Nursing Considerations
Fentanyl (Duragesic) Nursing Considerations
Ferrous Sulfate (Iron) Nursing Considerations
Fluoxetine (Prozac) Nursing Considerations
Fluticasone (Flonase) Nursing Considerations
Furosemide (Lasix) Nursing Considerations
Gabapentin (Neurontin) Nursing Considerations
Gentamicin (Garamycin) Nursing Considerations
Glipizide (Glucotrol) Nursing Considerations
Glucagon (GlucaGen) Nursing Considerations
Guaifenesin (Mucinex) Nursing Considerations
Haloperidol (Haldol) Nursing Considerations
Heparin (Hep-Lock) Nursing Considerations
Hepatitis B Vaccine for Newborns
Hydralazine (Apresoline) Nursing Considerations
Hydrochlorothiazide (Hydrodiuril) Nursing Considerations
Hydrocodone-Acetaminophen (Vicodin, Lortab) Nursing Considerations
Hydromorphone (Dilaudid) Nursing Considerations
Ibuprofen (Motrin) Nursing Considerations
Indomethacin (Indocin) Nursing Considerations
Insulin – Intermediate Acting (NPH) Nursing Considerations
Insulin – Long Acting (Lantus) Nursing Considerations
Insulin – Rapid Acting (Novolog, Humalog) Nursing Considerations
Insulin – Short Acting (Regular) Nursing Considerations
Iodine Nursing Considerations
Isoniazid (Niazid) Nursing Considerations
Ketorolac (Toradol) Nursing Considerations
Lactulose (Generlac) Nursing Considerations
Lamotrigine (Lamictal) Nursing Considerations
Levetiracetam (Keppra) Nursing Considerations
Levofloxacin (Levaquin) Nursing Considerations
Lidocaine (Xylocaine) Nursing Considerations
Lisinopril (Prinivil) Nursing Considerations
Lithium (Lithonate) Nursing Considerations
Loperamide (Imodium) Nursing Considerations
Lorazepam (Ativan) Nursing Considerations
Losartan (Cozaar) Nursing Considerations
Magnesium Sulfate (MgSO4) Nursing Considerations
Mannitol (Osmitrol) Nursing Considerations
Meperidine (Demerol) Nursing Considerations
Meropenem (Merrem) Nursing Considerations
Metformin (Glucophage) Nursing Considerations
Methadone (Methadose) Nursing Considerations
Methylergonovine (Methergine) Nursing Considerations
Methylphenidate (Concerta) Nursing Considerations
Methylprednisolone (Solu-Medrol) Nursing Considerations
Metoclopramide (Reglan) Nursing Considerations
Metoprolol (Toprol XL) Nursing Considerations
Metronidazole (Flagyl) Nursing Considerations
Midazolam (Versed) Nursing Considerations
Montelukast (Singulair) Nursing Considerations
Morphine (MS Contin) Nursing Considerations
Nalbuphine (Nubain) Nursing Considerations
Naproxen (Aleve) Nursing Considerations
Neostigmine (Prostigmin) Nursing Considerations
Nifedipine (Procardia) Nursing Considerations
Nitroglycerin (Nitrostat) Nursing Considerations
Nitroprusside (Nitropress) Nursing Considerations
Norepinephrine (Levophed) Nursing Considerations
Nystatin (Mycostatin) Nursing Considerations
Olanzapine (Zyprexa) Nursing Considerations
Omeprazole (Prilosec) Nursing Considerations
Ondansetron (Zofran) Nursing Considerations
Oxycodone (OxyContin) Nursing Considerations
Oxytocin (Pitocin) Nursing Considerations
Pancrelipase (Pancreaze) Nursing Considerations
Pantoprazole (Protonix) Nursing Considerations
Parasympatholytics (Anticholinergics) Nursing Considerations
Parasympathomimetics (Cholinergics) Nursing Considerations
Paroxetine (Paxil) Nursing Considerations
Pentobarbital (Nembutal) Nursing Considerations
Phenazopyridine (Pyridium) Nursing Considerations
Phenobarbital (Luminal) Nursing Considerations
Phenytoin (Dilantin) Nursing Considerations
Procainamide (Pronestyl) Nursing Considerations
Promethazine (Phenergan) Nursing Considerations
Propofol (Diprivan) Nursing Considerations
Propranolol (Inderal) Nursing Considerations
Propylthiouracil (PTU) Nursing Considerations
Quetiapine (Seroquel) Nursing Considerations
Ranitidine (Zantac) Nursing Considerations
Rifampin (Rifadin) Nursing Considerations
Salmeterol (Serevent) Nursing Considerations
Selegiline (Eldepyrl) Nursing Considerations
Sertraline (Zoloft) Nursing Considerations
Spironolactone (Aldactone) Nursing Considerations
Streptokinase (Streptase) Nursing Considerations
Sucralfate (Carafate) Nursing Considerations
Terbutaline (Brethine) Nursing Considerations
Tetracycline (Panmycin) Nursing Considerations
Trimethoprim-Sulfamethoxazole (Bactrim) Nursing Considerations
Uterine Stimulants (Oxytocin, Pitocin) Nursing Considerations
Vancomycin (Vancocin) Nursing Considerations
Vasopressin (Pitressin) Nursing Considerations
Verapamil (Calan) Nursing Considerations
Warfarin (Coumadin) Nursing Considerations
02.01 Hypertensive Crisis for CCRN Review