Anti-Infective – Lincosamide
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Outline
Overview
- Overview
- Antibacterial agents
- Mechanism of Action
- Inhibit protein synthesis
- Bacteriostatic or bactericidal
- Types
- Lincomycin
- Clindamycin
- Pirlimycin
- Indications
- Anaerobic infections
- Empyema
- Lung abscess
- Peritonitis
- Intra-abdominal infections
- Gram-positive cocci (strep/staph)
- Pharyngitis
- Otitis media
- Cellulitis
- Anaerobic infections
- Contraindications
- GI disease
- Colitis
- Enteritis
- GI disease
- Side Effects
- N / V / D
- C. difficile-associated diarrhea
- Metallic taste in mouth
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Transcript
Welcome back and today we are going to discuss lincosamides.
Now these types of medications are antibacterial and can be bacteriostatic or bactericidal, based on dosing. They work by inhibiting protein synthesis (interfering with communication – RNA/DNA). No communication will stop bacterial growth. Types of lincosamide include drugs ending in -MYCIN.
The indications are plentiful but I want you to focus on the groups, anaerobic (infections that lack oxygen and are often apart of normal bodily flora) and gram + cocci, which features many different types of infections. Empyema is pus-collection in the pleural space, while lung abscess is a pocket of infection in the lung. Peritonitis is inflammation of the abdominal wall. For anaerobic think lungs and gut. While Gram + cocci focus more on pharyngitis (sore throat), otitis media (ear infection) and cellulitis (skin infections).
All these side effects revolve around gastrointestinal issues? Why? Well, their alternation of the bowel flora. These medications clean hours, destroying good and bad flora, leaving the gut susceptible to such issues. Side effects are GI focused an include N/V/D, C diff (when you smell this, you will NOT forget it) and oddly enough a metallic taste in mouth. From what patients tell me, the taste lingers.
Priority nursing concepts for a patient receiving lincosamides include infection control and pharmacology.
Let’s review, lincosamides are antibacterial agents with ending with -MYCIN. Indications are anaerobic and gram + cocci infections (GA). As these antibiotics can cause GI issues, patients with GI issues are contraindicated from take this mediation. Side effects are GI focused with metallic taste being the outlier.
Now you know all you need to know about lincosamides. Now go out and be your best self and happy nursing!
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Pharmacology
Concepts Covered:
- Concepts of Pharmacology
- Test Taking Strategies
- Prefixes
- Suffixes
- Bipolar Disorders
- Immunological Disorders
- Medication Administration
- Learning Pharmacology
- Dosage Calculations
- Noninfectious Respiratory Disorder
- Anxiety Disorders
- Substance Abuse Disorders
- Adult
- Cardiac Disorders
- Cardiovascular Disorders
- Hematologic Disorders
- Central Nervous System Disorders – Brain
- Depressive Disorders
- Disorders of Pancreas
- Liver & Gallbladder Disorders
- Upper GI Disorders
- Urinary System
- Pregnancy Risks
- Microbiology
- Infectious Respiratory Disorder
- Respiratory Disorders
- Shock
- Male Reproductive Disorders
- Sexually Transmitted Infections
- Personality Disorders
- Psychotic Disorders
- Nervous System
- Labor Complications
- Postpartum Complications
- Prenatal Concepts
- Newborn Care
- Musculoskeletal Trauma
- Intraoperative Nursing
- Vascular Disorders
- Disorders of the Posterior Pituitary Gland
- Oncology Disorders
- EENT Disorders
- Emergency Care of the Cardiac Patient
- Female Reproductive Disorders
- Gastrointestinal Disorders
- Lower GI Disorders
- Neurologic and Cognitive Disorders
- Acute & Chronic Renal Disorders
- Urinary Disorders
- Disorders of the Adrenal Gland
- Integumentary Disorders
- Neurological
- Postoperative Nursing
- Peripheral Nervous System Disorders
- Disorders of the Thyroid & Parathyroid Glands
- Cardiovascular
Study Plan Lessons
Pharmacology Course Introduction
12 Points to Answering Pharmacology Questions
54 Common Medication Prefixes and Suffixes
Therapeutic Drug Levels (Digoxin, Lithium, Theophylline, Phenytoin)
Essential NCLEX Meds by Class
6 Rights of Medication Administration
Pharmacodynamics
Pharmacokinetics
The SOCK Method – Overview
The SOCK Method – S
The SOCK Method – O
The SOCK Method – C
The SOCK Method – K
Basics of Calculations
Oral Medications
Injectable Medications
IV Infusions (Solutions)
Complex Calculations (Dosage Calculations/Med Math)
Interactive Pharmacology Practice
Interactive Practice Drip Calculations
Pediatric Dosage Calculations
Disease Specific Medications
Antianxiety Meds
Benzodiazepines
ACLS (Advanced cardiac life support) Drugs
Anti-Platelet Aggregate
NG Tube Medication Administration
Coumarins
Thrombin Inhibitors
Thrombolytics
Anticonvulsants
Antidepressants
MAOIs
SSRIs
TCAs
Antidiabetic Agents
Insulin
Insulin – Mixtures (70/30)
Histamine 1 Receptor Blockers
Histamine 2 Receptor Blockers
Renin Angiotensin Aldosterone System
Sympatholytics (Alpha & Beta Blockers)
ACE (angiotensin-converting enzyme) Inhibitors
Angiotensin Receptor Blockers
Calcium Channel Blockers
Cardiac Glycosides
Anti-Infective – Aminoglycosides
Anti-Infective – Antifungals
Anti-Infective – Antitubercular
Anti-Infective – Antivirals
Anti-Infective – Carbapenems
Anti-Infective – Fluoroquinolones
Anti-Infective – Glycopeptide
Anti-Infective – Lincosamide
Anti-Infective – Macrolides
Anti-Infective – Penicillins and Cephalosporins
Anti-Infective – Sulfonamides
Anti-Infective – Tetracyclines
Atypical Antipsychotics
Antipsychotics
Autonomic Nervous System (ANS)
Sympathomimetics (Alpha (Clonodine) & Beta (Albuterol) Agonists)
Bronchodilators
Diuretics (Loop, Potassium Sparing, Thiazide, Furosemide/Lasix)
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Rh Immune Globulin in Pregnancy
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Eye Prophylaxis for Newborn
Phytonadione (Vitamin K) for Newborn
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Sedatives-Hypnotics
Barbiturates
Anesthetic Agents
Corticosteroids
Betamethasone and Dexamethasone in Pregnancy
Hydralazine
Nitro Compounds
Vasopressin
ACLS (Advanced cardiac life support) Drugs
Anti-Infective – Aminoglycosides
Anti-Infective – Carbapenems
Anti-Infective – Macrolides
Anti-Infective – Fluoroquinolones
Anti-Infective – Sulfonamides
Anti-Infective – Tetracyclines
Anti-Infective – Antifungals
Anti-Infective – Antivirals
Anti-Infective – Lincosamide
Thrombolytics
Anticonvulsants
Antidiabetic Agents
Sympatholytics (Alpha & Beta Blockers)
Anti-Infective – Antitubercular
Anti-Infective – Glycopeptide
Bronchodilators
Opioids
Barbiturates
Anesthetic Agents
Antineoplastics
Alkylating Agents
Antimetabolites
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Plant Alkaloids Topoisomerase and Mitotic Inhibitors
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Epidural
Insulin Drips
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02.01 Hypertensive Crisis for CCRN Review