Anti-Infective – Lincosamide
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Outline
Overview
- Overview
- Antibacterial agents
- Mechanism of Action
- Inhibit protein synthesis
- Bacteriostatic or bactericidal
- Types
- Lincomycin
- Clindamycin
- Pirlimycin
- Indications
- Anaerobic infections
- Empyema
- Lung abscess
- Peritonitis
- Intra-abdominal infections
- Gram-positive cocci (strep/staph)
- Pharyngitis
- Otitis media
- Cellulitis
- Anaerobic infections
- Contraindications
- GI disease
- Colitis
- Enteritis
- GI disease
- Side Effects
- N / V / D
- C. difficile-associated diarrhea
- Metallic taste in mouth
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Transcript
Welcome back and today we are going to discuss lincosamides.
Now these types of medications are antibacterial and can be bacteriostatic or bactericidal, based on dosing. They work by inhibiting protein synthesis (interfering with communication – RNA/DNA). No communication will stop bacterial growth. Types of lincosamide include drugs ending in -MYCIN.
The indications are plentiful but I want you to focus on the groups, anaerobic (infections that lack oxygen and are often apart of normal bodily flora) and gram + cocci, which features many different types of infections. Empyema is pus-collection in the pleural space, while lung abscess is a pocket of infection in the lung. Peritonitis is inflammation of the abdominal wall. For anaerobic think lungs and gut. While Gram + cocci focus more on pharyngitis (sore throat), otitis media (ear infection) and cellulitis (skin infections).
All these side effects revolve around gastrointestinal issues? Why? Well, their alternation of the bowel flora. These medications clean hours, destroying good and bad flora, leaving the gut susceptible to such issues. Side effects are GI focused an include N/V/D, C diff (when you smell this, you will NOT forget it) and oddly enough a metallic taste in mouth. From what patients tell me, the taste lingers.
Priority nursing concepts for a patient receiving lincosamides include infection control and pharmacology.
Let’s review, lincosamides are antibacterial agents with ending with -MYCIN. Indications are anaerobic and gram + cocci infections (GA). As these antibiotics can cause GI issues, patients with GI issues are contraindicated from take this mediation. Side effects are GI focused with metallic taste being the outlier.
Now you know all you need to know about lincosamides. Now go out and be your best self and happy nursing!
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Concepts Covered:
- Suffixes
- Concepts of Pharmacology
- Test Taking Strategies
- Med Term Basic
- Prefixes
- Med Term Whole
- Bipolar Disorders
- Immunological Disorders
- Medication Administration
- Learning Pharmacology
- Cardiovascular
- Emergency Care of the Cardiac Patient
- Terminology
- Cardiac Disorders
- Circulatory System
- Dosage Calculations
- Nervous System
- Skeletal System
- Shock
- Shock
- Noninfectious Respiratory Disorder
- Disorders of the Posterior Pituitary Gland
- Endocrine
- Disorders of Pancreas
- Disorders of the Thyroid & Parathyroid Glands
- Anxiety Disorders
- Hematology
- Substance Abuse Disorders
- Adult
- Gastrointestinal
- Upper GI Disorders
- Liver & Gallbladder Disorders
- Newborn Complications
- Lower GI Disorders
- Multisystem
- Cardiovascular Disorders
- Hematologic Disorders
- Central Nervous System Disorders – Brain
- Neurological
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- Renal
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- Microbiology
- Female Reproductive Disorders
- Infectious Respiratory Disorder
- Respiratory Disorders
- Neurologic and Cognitive Disorders
- Male Reproductive Disorders
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- Personality Disorders
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- Prenatal Concepts
- Newborn Care
- Musculoskeletal Trauma
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- Vascular Disorders
- Oncology Disorders
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- Gastrointestinal Disorders
- Acute & Chronic Renal Disorders
- Disorders of the Adrenal Gland
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- Renal Disorders
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- Peripheral Nervous System Disorders
Study Plan Lessons
Medical Terminology Course Introduction
Pharmacology Course Introduction
12 Points to Answering Pharmacology Questions
12 Points to Answering Pharmacology Questions
01.01 CCRN Test Overview for CCRN Review
MedTerm Basic Word Structure
54 Common Medication Prefixes and Suffixes
54 Common Medication Prefixes and Suffixes
MedTerm Body as a Whole
MedTerm Suffixes
Therapeutic Drug Levels (Digoxin, Lithium, Theophylline, Phenytoin)
Therapeutic Drug Levels (Digoxin, Lithium, Theophylline, Phenytoin)
Essential NCLEX Meds by Class
Essential NCLEX Meds by Class
MedTerm Prefixes
6 Rights of Medication Administration
6 Rights of Medication Administration
Pharmacodynamics
Pharmacokinetics
The SOCK Method – Overview
The SOCK Method – Overview
The SOCK Method – S
The SOCK Method – S
The SOCK Method – O
The SOCK Method – O
The SOCK Method – C
The SOCK Method – C
The SOCK Method – K
The SOCK Method – K
Basics of Calculations
Basics of Calculations
02.01 Hypertensive Crisis for CCRN Review
Neuro Terminology
Cardiac Terminology
02.02 Cardiomyopathy for CCRN Review
Dimensional Analysis Nursing (Dosage Calculations/Med Math)
Oral Medications
Oral Medications
Respiratory Terminology
02.03 Swan-Ganz Catheters for CCRN Review
Digestive Terminology
Injectable Medications
Injectable Medications
02.04 Pulmonary Artery Wedge Pressure (PAWP) for CCRN Review
02.05 Calculating PAWP on PEEP for CCRN Review
IV Infusions (Solutions)
IV Infusions (Solutions)
Urinary Terminology
Complex Calculations (Dosage Calculations/Med Math)
Complex Calculations (Dosage Calculations/Med Math)
02.06 Heart Murmurs for CCRN Review
Reproductive Terminology
Interactive Pharmacology Practice
Musculoskeletal Terminology
02.07 Reading “A, C, V Waves” & PAWP Waveforms for CCRN Review
02.08 Cardiac Catheterization & Acute Coronary Syndrome for CCRN Review
Interactive Practice Drip Calculations
Metabolic & Endocrine Terminology
02.09 12 Lead EKG- Leads 1, 2, 3, aVL, and aVF for CCRN Review
Hematology Oncology & Immunology Terminology
Pediatric Dosage Calculations
02.10 12 Lead EKG- Lead V1-V6 for CCRN Review
Integumentary (Skin) Terminology
02.11 12 Lead EKG- Injuries for CCRN Review
02.12 Myocardial Infarction- Inferior Wall for CCRN Review
02.13 Myocardial Infarction – Anterior Septal Wall for CCRN Review
02.14 Shock Stages for CCRN Review
02.15 Hypovolemic Shock for CCRN Review
02.16 Cardiogenic Shock for CCRN Review
02.17 Septic Shock for CCRN Review
02.18 Cardiovascular Practice Questions for CCRN Review
Disease Specific Medications
Sensory Terminology
03.01 Syndrome of Inappropriate Antidiuretic hormone (SIADH) for CCRN Review
03.02 Diabetes Insipidus for CCRN Review
Pharmacology Terminology
03.03 Hypoglycemia for CCRN Review
Psychiatry Terminology
Diagnostics Terminology
03.04 DKA vs HHNK for CCRN Review
03.05 Endocrine Practice Questions for CCRN Review
Procedural Terminology
Antianxiety Meds
04.01 Hematology for CCRN Review
Benzodiazepines
Benzodiazepines
04.02 Hematology Review Questions for CCRN Review
ACLS (Advanced cardiac life support) Drugs
05.01 Pancreatitis and Large Bowel Obstruction for CCRN Review
05.02 Liver Overview and Disease for CCRN Review
05.03 Jaundice for CCRN Review
05.04 Ruptured Spleen for CCRN Review
05.05 GI Practice Questions for CCRN Review
Anti-Platelet Aggregate
06.01 Organ Failure, Dysfunction & Trauma for CCRN Review
NG Tube Medication Administration
06.02 Poisoning for CCRN Review
Coumarins
06.03 Multi-System CCRN Important Points for CCRN Review
06.04 Differentiating Ectopy and Aberrancy for CCRN Review
Thrombin Inhibitors
06.05 Wide Complex Tachycardia for CCRN Review
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07.03 Uncal Herniation for CCRN Review
07.04 Supratentorial Herniation and Glasgow Coma Scale for CCRN Review
07.05 Supratentorial Herniation: Cushings Triad for CCRN Review
07.06 Increased Intracranial Pressure (ICP) for CCRN Review
07.07 Cerebral Perfusion Pressure for CCRN Review
07.08 Basilar Skull Fracture for CCRN Review
07.09 Meningitis for CCRN Review
07.10 Neurologic Review questions for CCRN Review
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08.01 Psychological Review for CCRN Review
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TCAs
09.01 Acute Renal Failure Overview for CCRN Review
Antidiabetic Agents
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09.04 Continuous Renal Replacement Therapy for CCRN Review
Insulin
Insulin
09.05 Chronic Renal Failure for CCRN Review
09.06 Renal Practice Questions for CCRN Review
Insulin – Mixtures (70/30)
10.01 Arterial Blood Gas (ABG) Interpretation for CCRN Review
Histamine 1 Receptor Blockers
Histamine 1 Receptor Blockers
10.02 Breath Sounds for CCRN Review
10.03 Acute Respiratory Failure for CCRN Review
Histamine 2 Receptor Blockers
Histamine 2 Receptor Blockers
10.04 Pulmonary Question Review for CCRN Review
Renin Angiotensin Aldosterone System
Renin Angiotensin Aldosterone System
Sympatholytics (Alpha & Beta Blockers)
ACE (angiotensin-converting enzyme) Inhibitors
ACE (angiotensin-converting enzyme) Inhibitors
Angiotensin Receptor Blockers
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Calcium Channel Blockers
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Cardiac Glycosides
Cardiac Glycosides
Anti-Infective – Aminoglycosides
Anti-Infective – Antifungals
Metronidazole (Flagyl) Nursing Considerations
Anti-Infective – Antitubercular
Anti-Infective – Antivirals
Anti-Infective – Carbapenems
Anti-Infective – Fluoroquinolones
Ciprofloxacin (Cipro) Nursing Considerations
Anti-Infective – Glycopeptide
Vancomycin (Vancocin) Nursing Considerations
Anti-Infective – Lincosamide
Anti-Infective – Macrolides
Anti-Infective – Penicillins and Cephalosporins
Anti-Infective – Penicillins and Cephalosporins
Anti-Infective – Sulfonamides
Anti-Infective – Tetracyclines
Atypical Antipsychotics
Atypical Antipsychotics
Antipsychotics
Autonomic Nervous System (ANS)
Autonomic Nervous System (ANS)
Sympathomimetics (Alpha (Clonodine) & Beta (Albuterol) Agonists)
Sympathomimetics (Alpha (Clonodine) & Beta (Albuterol) Agonists)
Parasympathomimetics (Cholinergics) Nursing Considerations
Parasympatholytics (Anticholinergics) Nursing Considerations
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Diuretics (Loop, Potassium Sparing, Thiazide, Furosemide/Lasix)
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Anti-Infective – Aminoglycosides
Anti-Infective – Carbapenems
Anti-Infective – Macrolides
Anti-Infective – Fluoroquinolones
Anti-Infective – Sulfonamides
Anti-Infective – Tetracyclines
Anti-Infective – Antifungals
Anti-Infective – Antivirals
Anti-Infective – Lincosamide
Thrombolytics
Anticonvulsants
Antidiabetic Agents
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Anti-Infective – Antitubercular
Anti-Infective – Glycopeptide
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Insulin Drips
ABG (Arterial Blood Gas) Interpretation-The Basics
ABG (Arterial Blood Gas) Oxygenation
ABG Course (Arterial Blood Gas) Introduction
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ABGs Tic-Tac-Toe interpretation Method
Acetaminophen (Tylenol) Nursing Considerations
Acyclovir (Zovirax) Nursing Considerations
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Hepatitis B Vaccine for Newborns
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Hydrocodone-Acetaminophen (Vicodin, Lortab) Nursing Considerations
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Metabolic Acidosis (interpretation and nursing diagnosis)
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Metformin (Glucophage) Nursing Considerations
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Methylergonovine (Methergine) Nursing Considerations
Methylphenidate (Concerta) Nursing Considerations
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Montelukast (Singulair) Nursing Considerations
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