Sepsis for Progressive Care Certified Nurse (PCCN)
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Outline
Sepsis
Definition/Etiology:
- Sepsis- abnormal inflammatory response resulting from an infection
Pathophysiology:
- Abnormal inflammatory response
- Changes to the vasculature
- SIRS criteria
Noticing: Assessment & Recognizing Cues:
- Prevention
- Treat infections early
- Recognize early decline
- Assessment
- AMS
- SIRS criteria
- HR up (or down)
- BP down
- RR up (or down)
- Temp up (or down)
- SpO2 down
Interpreting: Analyzing & Planning:
- Complete Blood Count (CBC)
- Basic/Complete Metabolic Panel (BMP/CMP)
- Renal
- Hepatic
- Lactate level (>2 or >4)
- Organ dysfunction
- Find/confirm the source of infection
- Chest x-ray/sputum culture (PNA)
- Urinalysis/culture (UTI)
- Blood cultures (Septicemia)
Responding: Patient Interventions & Taking Action:
- Antibiotics (maybe 2 or 3) QUICKLY!
- IV fluids A LOT!
- Decline further
Reflecting: Evaluating Patient Outcomes:
- High mortality and morbidity
- Early recognition is KEY!
Patient improvement:
- Vital signs stabilized
- Restored perfusion to organs (labs)
Continued treatment:
- Abx
Linchpins (Key Points):
- Sepsis ≠ septicemia
- Sepsis is an abnormal inflammatory response.
- Septicemia is an infection in the blood.
Transcript
References
- Mayo Clinic. (2022a). Diagnosis & treatment. Sepsis. https://www.mayoclinic.org/diseases-conditions/sepsis/diagnosis-treatment/drc-20351219.
- Mayo Clinic. (2022b). Symptoms & causes. Sepsis. https://www.mayoclinic.org/diseases-conditions/sepsis/symptoms-causes/syc-20351214
Adaptive Brain SIMCLEX Study Plan – 25 Sep 2025
Concepts Covered:
- Cardiac Disorders
- Integumentary Disorders
- Intraoperative Nursing
- Microbiology
- Substance Abuse Disorders
- Urinary Disorders
- Shock
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