Pharmacokinetics Nursing Mnemonic (ADME)
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Outline
ADME
- A-Absorption
- D-Distribution
- M-Metabolism
- E-Excretion
Description
“Add Me” – These are the 4 steps/components of pharmacokinetics, or how the body processes a drug. Absorption is getting the drug into the systemic circulation, Distribution is getting the drug to the target organs, Metabolism (performed by the Cytochrome P450 system) is making the drug active and excretable, and Excretion is the process of getting the drug (or its metabolites) out of the system.
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