Olanzapine (Zyprexa) Nursing Considerations

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Kara Tarr
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Drug Card Olanzapine (Zyprexa) (Cheatsheet)
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Outline

Generic Name

olanzapine

Trade Name

Zyprexa

Indication

schizophrenia, mania, depression, anorexia nervosa, nausea/vomiting related to chemotherapy

Action

antagonizes dopamine and serotonin

Therapeutic Class

antipsychotic, mood stabilizers

Pharmacologic Class

thienobenzodiazepines

Nursing Considerations

• do not use while breastfeeding
• can cause neurolyptic malignant syndrome, seizures, suicidal thoughts, insomnia, tardive
dyskinesia, agranulocytosis, constipation, tremors
• assess mental status
• monitor hemodynamics
• assess blood sugars
• assess intake and output
• monitor liver function tests

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Transcript

Hey guys, let’s talk about alanine, also known as Zyprexa. This is an oral medication, as you can see here with the tablets, and it also comes as an injection, the therapeutic class of Lanine or how it works in the body is an antipsychotic and also a mood stabilizer. The pharmacologic class, or the chemical effect of Lanine is a D benzodiazepine. So Lanine works by antagonizing dopamine in serotonin, which is why we use this drug for the management of schizophrenia, mania, depression, anorexia nervosa, and a also nausea and vomiting related to chemotherapy with Lanine. We can see side effects, including insomn suicidal thoughts, constipation, and also tremors. 

Let’s take a look at a few nursing considerations for alanine. Be sure to assess your patient’s mental status. Remember what this drug is used for. Also assess their blood sugar and intake an output while on alanine, your patient’s hemodynamics and liver function tests should be monitored. And alanine may cause in serious situations. Neuroleptic malignant syndrome, tardive dyskinesia seizures and a granulocyte hosts. It is important to know and teach that if your patient is breastfeeding, they should definitely not be taking this medication. So there is a black box warning for injectable Lanine patients receiving this medication injected should E in a healthcare facility only, and they should be observed for three hours following because alanine can cause post-injection delirium and sedation syndromes. That’s it for Lanine or Zyprexa. Now go out and be your best self today. And as always happy nursing.

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Psych Exam 3/2026

Concepts Covered:

  • Anxiety Disorders
  • Trauma-Stress Disorders
  • Bipolar Disorders
  • Depressive Disorders
  • Personality Disorders
  • Health & Stress
  • Eating Disorders
  • Psychotic Disorders
  • Psychological Emergencies
  • Psychological Disorders
  • Fundamentals of Emergency Nursing
  • Cognitive Disorders
  • Somatoform Disorders
  • Terminology
  • Medication Administration
  • Intraoperative Nursing
  • Neurologic and Cognitive Disorders
  • Substance Abuse Disorders
  • Emergency Care of the Trauma Patient
  • Multisystem

Study Plan Lessons

Anxiety
Anxiety Disorders (PTSD, Anxiety, Panic Attack) for Certified Emergency Nursing (CEN)
Generalized Anxiety Disorder
Nursing Case Study for Bipolar Disorder
Depression
Depression Concept Map
Dissociative Disorders
Health & Stress
Mood Disorders (Bipolar, Depression) for Certified Emergency Nursing (CEN)
Nursing Care Plan (NCP) for Anxiety
Nursing Care Plan (NCP) for Eating Disorders (Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder)
Nursing Care Plan (NCP) for Mood Disorders (Major Depressive Disorder, Bipolar Disorder)
Nursing Care Plan (NCP) for Personality Disorders
Nursing Care Plan (NCP) for Schizophrenia
Nursing Care Plan (NCP) for Suicidal Behavior Disorder
Nursing Case Study for Mania (Manic Syndrome)
Personality Disorders
Post-Traumatic Stress Disorder (PTSD)
Psychological Disorders
Stress and Crisis
Disruptive Behaviors, Aggression, Violence for Progressive Care Certified Nurse (PCCN)
Nursing Care Plan (NCP) for Dissociative Disorders
Nursing Care Plan (NCP) for Paranoid Disorders
Nursing Care Plan (NCP) for Post-Traumatic Stress Disorder (PTSD)
Nursing Case Study for Bipolar Disorder
Psychological Disorders
Psychological Disorders (Anxiety, Depression) for Progressive Care Certified Nurse (PCCN)
Hypochondriasis (Hypochondriac)
Psychiatry Terminology
Personality Disorders
Psychological Disorders
Nursing Care Plan (NCP) for Personality Disorders
Nursing Care Plan (NCP) for Eating Disorders (Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder)
Nursing Care Plan (NCP) for Personality Disorders
Nursing Care Plan (NCP) for Paranoid Disorders
Nursing Care Plan (NCP) for Schizophrenia
Nursing Care Plan (NCP) for Somatic Symptom Disorder (SSD)
Nursing Care Plan (NCP) for Suicidal Behavior Disorder
Paranoid Disorders
Personality Disorders
Psychological Disorders
Suicidal Behavior
Antidepressants
Barbiturates
Nursing Care Plan (NCP) for Somatic Symptom Disorder (SSD)
Nursing Case Study for (PTSD) Post Traumatic Stress Disorder
Psychiatry Terminology
SSRIs
TCAs
Bupropion (Wellbutrin) Nursing Considerations
Antidepressants
Alprazolam (Xanax) Nursing Considerations
Alcohol Withdrawal (Addiction)
Antipsychotics
Antipsychotics
Benzodiazepines
Benzodiazepines Nursing Mnemonic (Donuts and TLC)
Diazepam (Valium) Nursing Considerations
Lorazepam (Ativan) Nursing Considerations
Midazolam (Versed) Nursing Considerations
Nursing Care Plan (NCP) for Alcohol Withdrawal Syndrome / Delirium Tremens
Nursing Care Plan (NCP) for Mood Disorders (Major Depressive Disorder, Bipolar Disorder)
Nursing Case Study for (PTSD) Post Traumatic Stress Disorder
Nursing Case Study for Bipolar Disorder
Nursing Case Study for Head Injury
Nursing Case Study for Mania (Manic Syndrome)
Olanzapine (Zyprexa) Nursing Considerations
Substance Abuse (Alcohol, Drug Withdrawal) for Progressive Care Certified Nurse (PCCN)
Substance Abuse (Chronic Alcohol Abuse, Chronic Drug Abuse) for Progressive Care Certified Nurse (PCCN)
Toxic Ingestion, Inhalation, Overdose for Progressive Care Certified Nurse (PCCN)