Cholinergic Crisis – Signs and Symptoms Nursing Mnemonic (SLUDGE)
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Outline
SLUDGE
- S-Salivation
- L-Lacrimation
- U-Urination
- D-Defecation
- G-Gastric upset
- E-Emesis
Description
A cholinergic crisis can occur if the body stops properly breaking down Acetylcholine. This can cause overactivity of Acetylcholine at the neuromuscular junction. Acetylcholine is part of Rest & Digest (Parasympathetic) – so we see overactive digestion and secretion.
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