Alteplase (tPA, Activase) Nursing Considerations
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Outline
Generic Name
Alteplase
Trade Name
tPA, Activase
Indication
MI, acute ischemic stroke, occluded central lines
Action
Converts plasminogen to plasmin which degrades the fibrin found in clots
Therapeutic Class
Thrombolytics
Pharmacologic Class
Plasminogen activators
Nursing Considerations
• Contraindicated in active bleeding
• Monitor closely for signs of bleeding (petechiae)
○ q 15 min X1hr o q 15-30 min X 8 hr
• Use caution with patient who have had recent surgery
• May cause intracranial hemorrhage
• Monitor for anaphylaxis
• Use caution with uncontrolled hypertension
• Assess neuro status during therapy
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DRN 101, Week 9
Concepts Covered:
- Emergency Care of the Cardiac Patient
- Cardiac Disorders
- Cardiovascular
- Vascular Disorders
- Studying
- Hematologic Disorders
- Neurological Emergencies
- Central Nervous System Disorders – Brain
Study Plan Lessons
Acute Coronary Syndrome (ACS)
02.12 Myocardial Infarction- Inferior Wall for CCRN Review
02.08 Cardiac Catheterization & Acute Coronary Syndrome for CCRN Review
02.13 Myocardial Infarction – Anterior Septal Wall for CCRN Review
Acute Coronary Syndromes (MI-ST and Non ST, Unstable Angina) for Progressive Care Certified Nurse (PCCN)
Acute Inflammatory Disease (Myocarditis, Endocarditis, Pericarditis) for Progressive Care Certified Nurse (PCCN)
Alteplase (tPA, Activase) Nursing Considerations
Aneurysm (Dissecting, Repair) for Progressive Care Certified Nurse (PCCN)
Aneurysm and Dissection for Certified Emergency Nursing (CEN)
Aortic Aneurysm – Management Nursing Mnemonic (CRAM)
Aortic Aneurysm – Thoracic signs Nursing Mnemonic (PEE BADS)
Aortic Stenosis Symptoms Nursing Mnemonic (SAD)
ASA (Aspirin) Nursing Considerations
Bacterial Endocarditis – Symptoms Nursing Mnemonic (Be Joan Of Arc)
Bleeding Complications (Minor) Nursing Mnemonic (BEEP)
Bleeding Precautions Nursing Mnemonic (RANDI)
Cardiac Tamponade for Progressive Care Certified Nurse (PCCN)
Cardiac/Vascular Catheterization (Diagnostic, Interventional) for Progressive Care Certified Nurse (PCCN)
Cardiomyopathies (Dilated, Hypertrophic, Restrictive) for Progressive Care Certified Nurse (PCCN)
Cardiovascular Angiography
Cerebral Angiography
Clopidogrel (Plavix) Nursing Considerations
Coagulation Studies (PT, PTT, INR)
Coagulopathies, Medication-Induced (Coumadin, Platelet Inhibitors, Heparin, HIT) for Progressive Care Certified Nurse (PCCN)
Coronary Artery Disease Concept Map
Diltiazem (Cardizem) Nursing Considerations
Dysrhythmias Labs
Echocardiogram (Cardiac Echo)
HMG-CoA Reductase Inhibitors (Statins)
Myocardial Infarction Nursing Mnemonic (MONATAS)
Myocardial Infarction (MI) Case Study (45 min)
MI Surgical Intervention
Nursing Care and Pathophysiology of Coronary Artery Disease (CAD)
Nursing Care and Pathophysiology of Endocarditis and Pericarditis
Nursing Care and Pathophysiology of Myocardial Infarction (MI)
Nursing Care Plan (NCP) for Myocardial Infarction (MI)
Nursing Care Plan (NCP) for Pericarditis
Nursing Care Plan for Coronary Artery Disease (CAD)
Thrombin Inhibitors
To Clot or Not To Clot – Anticoagulants! – Live Tutoring Archive