Rh Immune Globulin in Pregnancy

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Outline

Overview

  1. Indication
    1. Given during pregnancy to prevent the Rh negative mother from developing antibodies against the fetus
    2. Given after delivery to prevent the Rh negative mother from developing antibodies that could attack a future pregnancy

Nursing Points

General

  1. Given to moms at 28 weeks and with in 72 hours of delivery
  2. Given to moms anytime there is a possibility blood mixture has occurred
    1. Pregnancy loss
    2. Ectopic pregnancy
    3. Injury to abdomen
      1. Fall
      2. Car accident
  3. IM injection
  4. See Lesson on Erythroblastosis Fetalis.

Assessment

  1. Verify Rh status of mother
    1. Only given to Rh negative patients
  2. Verify Rh status of newborn at delivery
    1. Cord blood
    2. Rh positive→ mother will receive Rhogam

Therapeutic Management

  1. Rhogam studies after delivery
  2. Rhogam given within 72 hours of delivery
    1. This is a blood product

Nursing Concepts

  1. Pharmacology
  2. Reproduction

Patient Education

  1. Why she is receiving
  2. IM injection

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Transcript

In this lesson I will explain Rh immune globulin and when it is given as well as your role in this care.

Ok let’s look at what this medication is. It is known as Rhogam. First let’s talk about what it is for. So we have learned that there are blood types that are incompatible. When blood types are not compatible the body makes antibodies. So this is given to a mother that has a Rh negative blood type to protect the fetus from making antibodies against maternal blood and to prevent the mother from making antibodies that would attack fetal blood. This will also be given to protect future pregnancies from being attacked by the maternal immune system. So when do we give it? It is given a few times. It is given at 28 weeks and then within 72 hours of delivery IF the newborn is Rh positive. If the newborn is negative then she doesn’t get it again. The mother will also be given this medication anytime there is a risk that blood mixture has occurred. So this would be in the event that there was a pregnancy loss, ectopic pregnancy or if there been trauma to the abdomen like a car accident or fall on the belly.

Our assessment is going to be to verify the Rh status of mother. Remember it is only given to Rh negative patients. We also will verify Rh status of newborn at delivery. Cord blood will be taken and if the newborn is Rh positive then the mother will receive Rhogam. If the newborn is negative then nothing further is needed. Management will be to draw rhogam studies on the patient the night after delivery if the newborn has been identified as positive. Remember its a blood product and the blood bank will need to get the right type so that is what the studies are for. We also just be to prepare patient and make her comfortable and this is an IM injection and a lot of medication so best to not give in the arm and do a big muscle group like the thigh.

Education will revolve on explaining why and what we are doing for the patient and letting her know where we will be injecting it.

Pharmacology is a concept because its medication and reproduction because this is needed to protect future pregnancies.

Ok so let’s review everything now. Rhogam is a blood product and it is is given to a mother that is Rh negative at 28 weeks, It is give again within 72 hours after delivery if the newborn is Rh positive. It is also given anytime there is a blood mixture. It is going to protect the moher from producing antibodies as that would cause an incompatibility if blood exposure occurs and also to protect a future pregnancy from being attacked by the maternal immune system.

Make sure you check out the resources attached to this lesson and review those key points. Now, go out and be your best selves today. And, as always, happy nursing.

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Pharmocology

Concepts Covered:

  • Test Taking Strategies
  • Prefixes
  • Suffixes
  • Bipolar Disorders
  • Immunological Disorders
  • Medication Administration
  • Urinary System
  • Cardiac Disorders
  • Personality Disorders
  • Nervous System
  • Substance Abuse Disorders
  • Cardiovascular Disorders
  • Respiratory Disorders
  • Pregnancy Risks
  • Hematologic Disorders
  • Liver & Gallbladder Disorders
  • Upper GI Disorders
  • Vascular Disorders
  • Disorders of Pancreas
  • Depressive Disorders
  • Urinary Disorders
  • Anxiety Disorders
  • Disorders of the Posterior Pituitary Gland
  • Noninfectious Respiratory Disorder
  • Concepts of Pharmacology
  • Dosage Calculations
  • Learning Pharmacology
  • Adult
  • Shock
  • Male Reproductive Disorders
  • Sexually Transmitted Infections
  • Microbiology
  • Emergency Care of the Cardiac Patient
  • Female Reproductive Disorders
  • Central Nervous System Disorders – Brain
  • Labor Complications
  • Musculoskeletal Trauma
  • EENT Disorders
  • Acute & Chronic Renal Disorders
  • Psychotic Disorders
  • Postpartum Complications
  • Prenatal Concepts
  • Intraoperative Nursing
  • Infectious Respiratory Disorder
  • Newborn Care
  • Oncology Disorders
  • Gastrointestinal Disorders
  • Neurologic and Cognitive Disorders
  • Integumentary Disorders
  • Disorders of the Adrenal Gland
  • Peripheral Nervous System Disorders
  • Postoperative Nursing
  • Neurological
  • Lower GI Disorders
  • Disorders of the Thyroid & Parathyroid Glands

Study Plan Lessons

12 Points to Answering Pharmacology Questions
54 Common Medication Prefixes and Suffixes
Therapeutic Drug Levels (Digoxin, Lithium, Theophylline, Phenytoin)
Essential NCLEX Meds by Class
6 Rights of Medication Administration
Renin Angiotensin Aldosterone System
ACE (angiotensin-converting enzyme) Inhibitors
Angiotensin Receptor Blockers
Atypical Antipsychotics
Autonomic Nervous System (ANS)
Benzodiazepines
Cardiac Glycosides
Corticosteroids
Calcium Channel Blockers
Diuretics (Loop, Potassium Sparing, Thiazide, Furosemide/Lasix)
Epoetin Alfa
Histamine 1 Receptor Blockers
Histamine 2 Receptor Blockers
Hydralazine
HMG-CoA Reductase Inhibitors (Statins)
Insulin
Magnesium Sulfate
MAOIs
NSAIDs
Nitro Compounds
Nitro Compounds
Parasympatholytics (Anticholinergics) Nursing Considerations
Anti-Infective – Penicillins and Cephalosporins
Proton Pump Inhibitors
SSRIs
TCAs
Vasopressin
Disease Specific Medications
NG Tube Medication Administration
Pharmacodynamics
Pharmacokinetics
Basics of Calculations
Dimensional Analysis Nursing (Dosage Calculations/Med Math)
Oral Medications
Injectable Medications
IV Infusions (Solutions)
Complex Calculations (Dosage Calculations/Med Math)
The SOCK Method – S
The SOCK Method – C
The SOCK Method – K
The SOCK Method – O
The SOCK Method – Overview
Sympathomimetics (Alpha (Clonodine) & Beta (Albuterol) Agonists)
ACLS (Advanced cardiac life support) Drugs
Parasympathomimetics (Cholinergics) Nursing Considerations
Anti-Infective – Aminoglycosides
Anti-Infective – Carbapenems
Anti-Infective – Macrolides
Anti-Infective – Fluoroquinolones
Anti-Infective – Sulfonamides
Anti-Infective – Tetracyclines
Anti-Infective – Antifungals
Anti-Infective – Antivirals
Acyclovir (Zovirax) Nursing Considerations
Adenosine (Adenocard) Nursing Considerations
Alendronate (Fosamax) Nursing Considerations
Alprazolam (Xanax) Nursing Considerations
Amiodarone (Pacerone) Nursing Considerations
Amitriptyline (Elavil) Nursing Considerations
Amlodipine (Norvasc) Nursing Considerations
Ampicillin (Omnipen) Nursing Considerations
Anti-Platelet Aggregate
Coumarins
Opioids
Amoxicillin (Amoxil) Nursing Considerations
Calcium Acetate (PhosLo) Nursing Considerations
Sympatholytics (Alpha & Beta Blockers)
Antianxiety Meds
Antipsychotics
Tocolytics
Mood Stabilizers
Uterine Stimulants (Oxytocin, Pitocin) Nursing Considerations
Meds for Postpartum Hemorrhage (PPH)
Opioid Analgesics in Pregnancy
Sedatives-Hypnotics
Betamethasone and Dexamethasone in Pregnancy
Anti-Infective – Antitubercular
Antidepressants
Thrombin Inhibitors
Hepatitis B Vaccine for Newborns
Phytonadione (Vitamin K) for Newborn
Eye Prophylaxis for Newborn
Lung Surfactant for Newborns
Prostaglandins in Pregnancy
Rh Immune Globulin in Pregnancy
Barbiturates
Anti-Infective – Lincosamide
Thrombolytics
Antidiabetic Agents
Anti-Infective – Glycopeptide
Anticonvulsants
Bronchodilators
Anesthetic Agents
ACLS (Advanced cardiac life support) Drugs
Anti-Infective – Aminoglycosides
Anti-Infective – Carbapenems
Anti-Infective – Macrolides
Anti-Infective – Fluoroquinolones
Anti-Infective – Sulfonamides
Anti-Infective – Tetracyclines
Anti-Infective – Antifungals
Anti-Infective – Antivirals
Anti-Infective – Lincosamide
Thrombolytics
Anticonvulsants
Antidiabetic Agents
Sympatholytics (Alpha & Beta Blockers)
Anti-Infective – Antitubercular
Anti-Infective – Glycopeptide
Bronchodilators
Opioids
Barbiturates
Anesthetic Agents
Epidural
Patient Controlled Analgesia (PCA)
Insulin Drips
Interactive Practice Drip Calculations
Interactive Pharmacology Practice
Plant Alkaloids Topoisomerase and Mitotic Inhibitors
Pediatric Dosage Calculations
Alkylating Agents
Antimetabolites
Antineoplastics
Anti Tumor Antibiotics
Captopril (Capoten) Nursing Considerations
Azithromycin (Zithromax) Nursing Considerations
Bisacodyl (Dulcolax) Nursing Considerations
Diphenoxylate-Atropine (Lomotil) Nursing Considerations
ASA (Aspirin) Nursing Considerations
Acetaminophen (Tylenol) Nursing Considerations
Atenolol (Tenormin) Nursing Considerations
Atorvastatin (Lipitor) Nursing Considerations
Atropine (Atropen) Nursing Considerations
Benztropine (Cogentin) Nursing Considerations
Bupropion (Wellbutrin) Nursing Considerations
Buspirone (Buspar) Nursing Considerations
Dobutamine (Dobutrex) Nursing Considerations
Epinephrine (EpiPen) Nursing Considerations
Escitalopram (Lexapro) Nursing Considerations
Dexamethasone (Decadron) Nursing Considerations
Dopamine (Inotropin) Nursing Considerations
Lorazepam (Ativan) Nursing Considerations
Diltiazem (Cardizem) Nursing Considerations
Diphenhydramine (Benadryl) Nursing Considerations
Divalproex (Depakote) Nursing Considerations
Epoetin (Epogen) Nursing Considerations
Erythromycin (Erythrocin) Nursing Considerations
Famotidine (Pepcid) Nursing Considerations
Fentanyl (Duragesic) Nursing Considerations
Carbamazepine (Tegretol) Nursing Considerations
Cefaclor (Ceclor) Nursing Considerations
Ciprofloxacin (Cipro) Nursing Considerations
Cefdinir (Omnicef) Nursing Considerations
Clopidogrel (Plavix) Nursing Considerations
Codeine (Paveral) Nursing Considerations
Cortisone (Cortone) Nursing Considerations
Cyclosporine (Sandimmune) Nursing Considerations
Lisinopril (Prinivil) Nursing Considerations
Losartan (Cozaar) Nursing Considerations
Iodine Nursing Considerations
Nifedipine (Procardia) Nursing Considerations
Isoniazid (Niazid) Nursing Considerations
Metronidazole (Flagyl) Nursing Considerations
Nystatin (Mycostatin) Nursing Considerations
Fluticasone (Flonase) Nursing Considerations
Levofloxacin (Levaquin) Nursing Considerations
Hydralazine (Apresoline) Nursing Considerations
Nitroprusside (Nitropress) Nursing Considerations
Haloperidol (Haldol) Nursing Considerations
Olanzapine (Zyprexa) Nursing Considerations
Nitroglycerin (Nitrostat) Nursing Considerations
Norepinephrine (Levophed) Nursing Considerations
Neostigmine (Prostigmin) Nursing Considerations
Meropenem (Merrem) Nursing Considerations
Morphine (MS Contin) Nursing Considerations
Magnesium Sulfate (MgSO4) Nursing Considerations
Meperidine (Demerol) Nursing Considerations
Methylphenidate (Concerta) Nursing Considerations
Guaifenesin (Mucinex) Nursing Considerations
Hydrochlorothiazide (Hydrodiuril) Nursing Considerations
Montelukast (Singulair) Nursing Considerations
Mannitol (Osmitrol) Nursing Considerations
Loperamide (Imodium) Nursing Considerations
Metoclopramide (Reglan) Nursing Considerations
Lactulose (Generlac) Nursing Considerations
Pancrelipase (Pancreaze) Nursing Considerations
Ondansetron (Zofran) Nursing Considerations
Omeprazole (Prilosec) Nursing Considerations
Pantoprazole (Protonix) Nursing Considerations
Glucagon (GlucaGen) Nursing Considerations
Lithium (Lithonate) Nursing Considerations
Lidocaine (Xylocaine) Nursing Considerations
Ibuprofen (Motrin) Nursing Considerations
Indomethacin (Indocin) Nursing Considerations
Ketorolac (Toradol) Nursing Considerations
Naproxen (Aleve) Nursing Considerations
Methylergonovine (Methergine) Nursing Considerations
Oxytocin (Pitocin) Nursing Considerations
Hydromorphone (Dilaudid) Nursing Considerations
Hydromorphone (Dilaudid) Nursing Considerations
Methadone (Methadose) Nursing Considerations
Nalbuphine (Nubain) Nursing Considerations
Oxycodone (OxyContin) Nursing Considerations
Digoxin (Lanoxin) Nursing Considerations
Enalapril (Vasotec) Nursing Considerations
Enoxaparin (Lovenox) Nursing Considerations
Fluoxetine (Prozac) Nursing Considerations
Furosemide (Lasix) Nursing Considerations
Gabapentin (Neurontin) Nursing Considerations
Gentamicin (Garamycin) Nursing Considerations
Calcium Carbonate (Tums) Nursing Considerations
Glipizide (Glucotrol) Nursing Considerations
Carbidopa-Levodopa (Sinemet) Nursing Considerations
Celecoxib (Celebrex) Nursing Considerations
Cephalexin (Keflex) Nursing Considerations
Chlorpromazine (Thorazine) Nursing Considerations
Cimetidine (Tagamet) Nursing Considerations
Clindamycin (Cleocin) Nursing Considerations
Diazepam (Valium) Nursing Considerations
Bismuth Subsalicylate (Pepto-Bismol) Nursing Considerations
Midazolam (Versed) Nursing Considerations
Lamotrigine (Lamictal) Nursing Considerations
Heparin (Hep-Lock) Nursing Considerations
Metformin (Glucophage) Nursing Considerations
Insulin – Rapid Acting (Novolog, Humalog) Nursing Considerations
Insulin – Short Acting (Regular) Nursing Considerations
Insulin – Intermediate Acting (NPH) Nursing Considerations
Insulin – Mixtures (70/30)
Insulin – Long Acting (Lantus) Nursing Considerations
Albuterol (Ventolin) Nursing Considerations
Quetiapine (Seroquel) Nursing Considerations
Ferrous Sulfate (Iron) Nursing Considerations
Vasopressin (Pitressin) Nursing Considerations
Propofol (Diprivan) Nursing Considerations
Phenazopyridine (Pyridium) Nursing Considerations
Methylprednisolone (Solu-Medrol) Nursing Considerations
Sertraline (Zoloft) Nursing Considerations
Pentobarbital (Nembutal) Nursing Considerations
Alteplase (tPA, Activase) Nursing Considerations
Rifampin (Rifadin) Nursing Considerations
Phenytoin (Dilantin) Nursing Considerations
Verapamil (Calan) Nursing Considerations
Procainamide (Pronestyl) Nursing Considerations
Ranitidine (Zantac) Nursing Considerations
Propylthiouracil (PTU) Nursing Considerations
Metoprolol (Toprol XL) Nursing Considerations
Tetracycline (Panmycin) Nursing Considerations
Streptokinase (Streptase) Nursing Considerations
Selegiline (Eldepyrl) Nursing Considerations
Warfarin (Coumadin) Nursing Considerations
Sucralfate (Carafate) Nursing Considerations
Spironolactone (Aldactone) Nursing Considerations
Salmeterol (Serevent) Nursing Considerations
Propranolol (Inderal) Nursing Considerations
Vancomycin (Vancocin) Nursing Considerations
Trimethoprim-Sulfamethoxazole (Bactrim) Nursing Considerations
Terbutaline (Brethine) Nursing Considerations
Hydrocodone-Acetaminophen (Vicodin, Lortab) Nursing Considerations
Promethazine (Phenergan) Nursing Considerations
Paroxetine (Paxil) Nursing Considerations
Phenobarbital (Luminal) Nursing Considerations
Levetiracetam (Keppra) Nursing Considerations
Butorphanol (Stadol) Nursing Considerations