Nursing Care and Pathophysiology for Cushings Syndrome
Overview Hypersecretion of glucocorticoids leading to elevated cortisol levels A greater incidence in women Life-threatening if untreated Nursing Points General Causes Adrenal or Pituitary Tumor The pituitary gland controls adrenal hormones Overuse or Chronic use of Corticosteroids Adrenal Cortex Glucocorticoids Cortisol Glucose & Fat Metabolism Anti-inflammatory Mineralocorticoids Aldosterone Regulate fluid and electrolytes Sex hormones (Androgens) […]
Addisons Disease

Pathophysiology: Addison’s occurs because there is an elevated level of serum ACTH and inadequate amounts of corticosteroids. Overview Hyposecretion of adrenal cortex hormones Decreased levels of glucocorticoids and mineralocorticoids leads to Electrolyte imbalances Decreased vascular volume Fatal if untreated Nursing Points General Adrenal Cortex Glucocorticoids Cortisol Glucose & Fat Metabolism Anti-inflammatory Mineralocorticoids Aldosterone Regulate fluid […]
Metabolic & Endocrine Module Intro
Upon completion of this module, you will be able to… Discuss the pathophysiology of adrenal disorders and differences between Addison’s Disease and Cushing’s Syndrome Discuss the impact of ADH on the body and the differences between Diabetes Insipidus and Syndrome of Inappropriate Antidiuretic Hormone Discuss the pathophysiology of thyroid disorders and the differences between Hyperthyroidism […]
Metabolic/Endocrine Course Introduction
The Metabolic and Endocrine Course reviews the major organs and glands involved in secreting hormones in our bodies. Hormones are responsible for regulating nearly every basic function of our body, like our heart rate and processing blood sugar. This course breaks down what happens when each gland is overactive or underactive. We will also walk […]
Cerebral Metabolism
Overview The brain has very high perfusion and energy (glucose) requirements. Nursing Points General Perfusion requirements The brain uses: 20% of total cardiac output (CO) 20% of total delivered oxygen (DO2) VERY sensitive to changes in CO or DO2 Monitor Mean Arterial Pressure (MAP), Cerebral Perfusion Pressure (CPP), PaO2 and SpO2 Energy requirements Massive energy […]
Insulin
Overview Types of Insulin Rapid Acting Aspart (Novolog) Onset- 10-20 minutes Peak – 1-3 hours Duration – 3-5 hours Lispro Onset- 5-15 minutes Peak- 1-1.5 hours Duration- 3-4 hours Glulisine- rare Short Acting Humulin R and Novolin R Onset- 30-60 minutes Peak- 1-5 hours Duration- 6-10 hours Intermediate Acting NPH or Humulin N Onset- 1-2 […]
Vasopressin
Overview Indications Diabetes Insipidus Lack of ADH Resection of posterior pituitary gland Low blood pressure Patho background Anti-diuretic hormone (ADH) = Vasopressin Vasopressin is secreted from the posterior pituitary gland. Factors that cause the release of vasopressin in the body Hypovolemia Blood loss Low blood pressure Low kidney perfusion Mechanism of action Causes kidneys to […]
Hypotonic Solutions
Hypotonic solutions will cause fluid to rush into the cells, causing them to swell and putting them at risk for lysis.
Hypertonic Solutions
Hypertonic solutions will cause fluid to rush out of the cells, causing them to shrink and risking severe cellular dehydration
Facial Symptoms of Hypothyroidism
Hypothyroidism can cause expressionless face, puffy eyes, and swelling around the face and neck