Ranitidine (Zantac) Nursing Considerations
Generic Name ranitidine Trade Name Zantac Indication duodenal ulcers, GERD, heartburn, esophagitis, GI bleed Action inhibits action of histamine in gastric parietal cells, decreases gastric acid secretion Therapeutic Class antiulcer agents Pharmacologic Class histamine H2 antagonists Nursing Considerations • may cause arrhythmias, agranulocytosis, aplastic anemia, confusion • assess abdominal pain • monitor for blood in […]
Verapamil (Calan) Nursing Considerations
Generic Name verapamil Trade Name Isoptin Indication hypertension, angina, SVT, migraine Action prevents transport of calcium, leading to decreased contraction, decreases SA and AV node conduction Therapeutic Class antianginals, antiarrhythmic, antihypertensive, vascular headache suppressants Pharmacologic Class Ca Channel Blocker Nursing Considerations • don’t use with 2nd and 3rd degree heartblock • don’t use with systolic […]
Nystatin (Mycostatin) Nursing Considerations
Generic Name nystatin Trade Name Mycostatin Indication candidiasis, denture stomatitis Action causes leakage of fungal cell contents Therapeutic Class Antifungal Pharmacologic Class none Nursing Considerations • may cause diarrhea, nausea, vomiting • can be used to soak dentures • assess mucus membrane
Glipizide (Glucotrol) Nursing Considerations
Generic Name Glipizide Trade Name Glucotrol Indication Type 2 diabetes mellitus Action Stimulates release of insulin from the beta cells in the pancreases and leads to increased sensitivity to insulin Therapeutic Class Anti-diabetic Pharmacologic Class Sulfonylureas Nursing Considerations • May cause aplastic anemias, hypoglycemia, photosensitivity, dizziness, drowsiness, headache, diarrhea • Monitor CBC, assess for allergy […]
Procainamide (Pronestyl) Nursing Considerations
Generic Name procainamide Indication wide variety ventricular and atrial arrhythmias, PAC, PVC, VTach, post cardioversion Action decreases excitability and slows conduction velocity through the heart Therapeutic Class antiarrhythmic (Class IA Na Channel Blocker) Nursing Considerations • may cause ventricular arrhythmias, seizure, asystole, heart block • monitor EKG continuously may cause widening of QRS complex • […]
Streptokinase (Streptase) Nursing Considerations
Generic Name streptokinase Trade Name Streptase Indication pulmonary embolism, DVT, occluded lines, arterial thrombus Action converts plasminogen to plasmin which degrades fibrin clots Therapeutic Class Thrombolytic Pharmacologic Class plasminogen activators Nursing Considerations • contraindicated with active bleeding, hypersensitivity, bronchospasm, intracranial hemorrhage, hypotension • begin therapy as soon as possible • monitor vital signs continuously • […]
Insulin – Mixtures (70/30)
Generic Name Lispro mixture, Aspart mixture, NPH/regular Trade Name Humalog Mix, NovoLog Mix, Humulin 70/30, Novolin 70/30 Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver, prevents breakdown of fat and protein Route Onset Peak Duration Lispro […]
Cyclosporine (Sandimmune) Nursing Considerations
Generic Name Cyclosporine Trade Name Sandimmune Indication Prevention of rejection in transplantation, treatment of severe RA, management of ulcerative colitis Action Inhibits normal immune response primarily by decreasing the activity of T cells Therapeutic Class Immunosuppressant, antirheumatics (DMARD) Pharmacologic Class Polypeptides (cyclic) Nursing Considerations • May cause seizures, tremors, hypertension, hepatotoxicity, diarrhea, N/V, gingival hyperplasia […]
Diphenoxylate-Atropine (Lomotil) Nursing Considerations
Generic Name Diphenoxylate/atropine Trade Name Lomotil Indication Treatment for diarrhea Action Inhibits GI motility via anticholinergic effects Therapeutic Class Antidiarrheal Pharmacologic Class Anticholinergic Nursing Considerations • Contraindicated with angle-closure glaucoma, dehydration • Structurally related to opioids so use caution with patients that have allergies to opioids • May cause constipation, tachycardia, dizziness, ileus • Monitor […]
Fentanyl (Duragesic) Nursing Considerations
Generic Name Fentanyl Trade Name Sublimaze Indication Supplement to general anesthesia, continuous IV infusion for purpose of analgesia Action Binds to opiate receptors in CNS altering perception of pain, producing CNS depression Therapeutic Class Opioid Analgesic Pharmacologic Class Opioid agonists Nursing Considerations • Use caution with increased ICP, head trauma, adrenal insufficiency • Avoid use […]