Streptokinase (Streptase) Nursing Considerations
Generic Name streptokinase Trade Name Streptase Indication pulmonary embolism, DVT, occluded lines, arterial thrombus Action converts plasminogen to plasmin which degrades fibrin clots Therapeutic Class Thrombolytic Pharmacologic Class plasminogen activators Nursing Considerations • contraindicated with active bleeding, hypersensitivity, bronchospasm, intracranial hemorrhage, hypotension • begin therapy as soon as possible • monitor vital signs continuously • […]
Insulin – Mixtures (70/30)
Generic Name Lispro mixture, Aspart mixture, NPH/regular Trade Name Humalog Mix, NovoLog Mix, Humulin 70/30, Novolin 70/30 Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver, prevents breakdown of fat and protein Route Onset Peak Duration Lispro […]
Cyclosporine (Sandimmune) Nursing Considerations
Generic Name Cyclosporine Trade Name Sandimmune Indication Prevention of rejection in transplantation, treatment of severe RA, management of ulcerative colitis Action Inhibits normal immune response primarily by decreasing the activity of T cells Therapeutic Class Immunosuppressant, antirheumatics (DMARD) Pharmacologic Class Polypeptides (cyclic) Nursing Considerations • May cause seizures, tremors, hypertension, hepatotoxicity, diarrhea, N/V, gingival hyperplasia […]
Diphenoxylate-Atropine (Lomotil) Nursing Considerations
Generic Name Diphenoxylate/atropine Trade Name Lomotil Indication Treatment for diarrhea Action Inhibits GI motility via anticholinergic effects Therapeutic Class Antidiarrheal Pharmacologic Class Anticholinergic Nursing Considerations • Contraindicated with angle-closure glaucoma, dehydration • Structurally related to opioids so use caution with patients that have allergies to opioids • May cause constipation, tachycardia, dizziness, ileus • Monitor […]
Fentanyl (Duragesic) Nursing Considerations
Generic Name Fentanyl Trade Name Sublimaze Indication Supplement to general anesthesia, continuous IV infusion for purpose of analgesia Action Binds to opiate receptors in CNS altering perception of pain, producing CNS depression Therapeutic Class Opioid Analgesic Pharmacologic Class Opioid agonists Nursing Considerations • Use caution with increased ICP, head trauma, adrenal insufficiency • Avoid use […]
Benztropine (Cogentin) Nursing Considerations
Generic Name Benztropine Trade Name Cogentin Indication Treatment for Parkinson’s disease Action Exhibits anticholinergic properties (blocks acetylcholine) in the CNS to reduce rigidity and tremors Therapeutic Class Antiparkinson agent Pharmacologic Class Anticholinergic Nursing Considerations • May lead to arrhythmias, hypotension, palpitations, and tachycardia • Anticholinergic effects like constipation, dry mouth • Assess for extrapyramidal symptoms […]
Bisacodyl (Dulcolax) Nursing Considerations
Generic Name Bisacodyl Trade Name Dulcolax Indication Treatment of constipation, bowel regimen Action Stimulates enteric nerves to cause peristalsis which leads to fluid accumulation in the colon Therapeutic Class Laxatives Pharmacologic Class Stimulant laxatives Nursing Considerations • May lead to hypokalemia • May cause abdominal pain and cramps • Not for use within 1 hour […]
Buspirone (Buspar) Nursing Considerations
In this lesson we will cover Buspirone nursing considerations: Generic Name Buspirone Trade Name Buspar Indication Management of anxiety Action Relieves anxiety by binding to dopamine and serotonin receptors Therapeutic Class Antianxiety Pharmacologic Class Azapirone Buspirone Nursing Considerations • Do not administer concurrently with MAOI or grapefruit juice • May lead to dizziness, drowsiness, fatigue, […]
Carbidopa-Levodopa (Sinemet) Nursing Considerations
Generic Name Carbidopa/levodopa Trade Name Sinemet Indication Parkinson’s disease Action Levodopa is converted to dopamine and works as a neurotransmitter, carbidopa prevents the destruction of levodopa allowing it to cross the blood brain barrier Therapeutic Class Antiparkinson agent Pharmacologic Class Dopamine Agonist Nursing Considerations • May cause orthostatic hypotension • May cause dark urine • […]
Cefdinir (Omnicef) Nursing Considerations
Generic Name Cefdinir Trade Name Omnicef Indication Treatment of skin infections, otitis media Action Bactericidal, binds to bacterial cell wall causing cell death Therapeutic Class Anti-infectives Pharmacologic Class Cephalosporin 3rd generations Nursing Considerations • Contraindicated in cephalosporin and possibly penicillin allergies • May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis at IV site, anaphylaxis […]